[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"infusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:infusion":88},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,68],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100586074",false,"NCT06910644","Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy","Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 75 years.\n* American Society of Anesthesiologists (ASA) physical status II.\n* Scheduled for mastectomy with axillary dissection (either modified radical mastectomy with or without latissimus dorsi flap or conservative breast surgery) due to breast cancer.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Known allergy to any of the study drugs.\n* Those with hepatic or renal insufficiency.\n* Patients who are running regularly on B blockers.\n* α2 adrenergic agonists and sedatives.\n* Psychoactive medications.","FEMALE","18 Years","75 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to compare dexmedetomidine and lidocaine infusions as adjuvants to general anesthesia for chronic pain management after mastectomy.",[26,27,28,29,30,31,32],"Dexmedetomidine","Lidocaine","Infusion","Adjuvants","General Anesthesia","Chronic Pain","Mastectomy","RECRUITING","2025-04-05",{"date":36,"type":37},"2025-04-08","ACTUAL",{"date":34,"type":37},{"date":40,"type":20},"2025-12-01",{"name":42,"class":43},"Cairo University","OTHER",1,{"id":46,"slug":4,"hasResults":10,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":10,"sex":51,"minAge":16,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":64,"leadSponsor":66,"locationsCount":44},"100581319","NCT06848764","Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery","A Randomized Double-Blind Trial Comparing Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Patients Undergoing Functional Endoscopic Sinus Surgery","Inclusion Criteria:\n\n* Age from 18 to 65 years old.\n* American Society of Anesthesiologists (ASA) physical status I - II.\n* Scheduled for elective functional endoscopic sinus surgery.\n\nExclusion Criteria:\n\n* Diabetes mellitus.\n* Coagulation disorders.\n* Kidney and liver dysfunction.\n* Cerebrovascular disease.\n* Cardiovascular problems.\n* High blood pressure.\n* Asthma.\n* Chronic obstructive pulmonary disease (COPD).\n* End organ damage.\n* Psychosis.\n* Taking antipsychotic drugs.\n* Allergy to study drugs.\n* Substance abuse.\n* Taking beta blockers.\n* Heart rate of \\\u003C 55 beat\u002Fminute.","ALL","65 Years",{"count":54,"type":20},40,[23],"This work aims to compare lidocaine and dexmedetomidine infusions for intraoperative bleeding in patients undergoing functional endoscopic sinus surgery.",[27,26,28,58,59],"Intraoperative Bleeding","Functional Endoscopic Sinus Surgery","2025-03-01",{"date":62,"type":37},"2025-03-05",{"date":60,"type":37},{"date":65,"type":20},"2025-09-01",{"name":67,"class":43},"Ain Shams University",{"id":69,"slug":4,"hasResults":10,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":10,"sex":51,"minAge":16,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":76,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":85,"leadSponsor":87,"locationsCount":44},"100580455","NCT06837519","Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery","A Randomized Double-Blind Trial Comparing Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery","Inclusion Criteria:\n\n* Age ≥18 years old.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status of I, II.\n* Patients undergoing video-assisted thoracoscopic surgery (VATS) under general anesthesia.\n\nExclusion Criteria:\n\n* Hypersensitivity to any of the used drugs.\n* Coagulation disorder.\n* Body mass index \\>35 kg\u002Fm2.\n* History of chronic pain requiring daily opioids\u002Fsteroids\u002Fclonidine\u002Fother α2 agonist\u002Fanalgesics or any drugs acting on the central nervous system during the previous 2 weeks, and drug\u002Falcohol abuse.\n* Contraindication to the use of local anesthetics.\n* Cardiovascular disease.\n* Severe respiratory, renal or hepatic impairment.\n* Insulin-dependent diabetes mellitus.\n* Central nervous system or psychiatric disease.",{"count":75,"type":20},75,[23],"This study aims to compare lidocaine and dexmedetomidine infusion and their combination on perioperative pain in patients undergoing video-assisted thoracoscopic surgery.",[27,26,28,79,80],"Perioperative Pain","Video-Assisted Thoracoscopic Surgery","2025-02-20",{"date":83,"type":37},"2025-02-21",{"date":81,"type":37},{"date":86,"type":20},"2025-08-01",{"name":67,"class":43},""]