Injury

5

Review clinical trials related to Injury. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical Evaluation of an AI Risk Prediction System (AI-TRiPS)

The goal of this clinical study is to evaluate a software device and its impact on clinician behaviour during the initial management of trauma patients in a real-world clinical setting. Known as the AI-TRiPS Device this software uses real-time prehospital data and machine learning-based risk predictions which are displayed digitally for hospital trauma teams prior patient arrival. The investigators will use a Stepped Wedge Cluster Randomised Controlled study design with an integrated process evaluation. The Device will be deployed across the London Major Trauma System where the Major Trauma Centres will be the clusters. Each cluster will transition from control (standard care) to intervention at a pre-specified time (time of transition is randomised). Primary Outcome: Clinician behaviour, assessed via the accuracy of risk prediction and clinician confidence. Secondary Outcome: Clinician acceptability, care process metrics, patient outcomes, and safety endpoints. Primary study population: Hospital trauma clinicians, following initial resuscitation of each eligible trauma patient, who will complete electronic questionnaires. Secondary study population: Adult trauma patients, data will be collected for the duration of their index admission to hospital, to assess outcomes and enable comparison with clinician risk predictions.

Participants needed: 1,200
Trial details
Phase: Early Phase 1Age: 16+Biological sex: AllType: InterventionalSponsor: Queen Mary University of LondonUpdated: Jun 8, 2026
Eligibility criteria

Senior clinical decision-maker involved in the initial trauma resuscitation (e.g... [+6]

Aged under 16 [+5]

Status: Not yet recruiting

Data-Driven Lay First Responder Program in Cameroon

Cameroon experiences a high burden of injury-related morbidity and mortality and currently lacks a formal pre-hospital care system. Lay First Responder (LFR) programs have been implemented in several low-and middle-income countries to improve early injury care by training non-medical community members with high exposure to injury, such as commercial drivers, in basic first aid and safe transport of injured patients. The study aims to implement and evaluate a data-driven, context-adapted LFR program in Cameroon using an implementation science approach. Quantitative trauma registry data and qualitative stakeholder interviews will be used to adapt the LFR curriculum to local injury patterns and care gaps. LFR program implementation will be associated with increased chances of survival on presentation and improved trauma outcomes. The study is an interrupted time series evaluation of an LFR intervention where prehospital care rates and clinical patterns in the Cameroon Trauma Registry (CTR) patients at Limbe Regional hospital will be compared between historical pre-implementation controls and post-implementation of a data-driven lay first responder training program (the intervention).

Participants needed: 1,812
Trial details
Biological sex: AllType: InterventionalSponsor: Sabrinah ChristieUpdated: May 12, 2026Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

The Relationship Between Training Dynamics and General Health Status in Veteran Football Players

The goal of this observational study is to learn how training habits and general health status are related to injury risk in veteran football players (men over 35 years old who play recreational football). The main questions it aims to answer are: Do specific training patterns (such as frequency, intensity, and duration) increase or lower the risk of injury? How does general health status (including factors like sleep, nutrition, and existing health conditions) affect injury risk? Participants will: Complete questionnaires about their training habits, lifestyle, and general health Report any injuries they experience during the football season Attend periodic health assessments

Participants needed: 130
Trial details
Age: 40+Biological sex: MaleType: ObservationalSponsor: Izmir Bakircay UniversityUpdated: Jan 30, 2026Locations: 1
Eligibility criteria

Playing football as a veteran

Not participating in a regular training program

Status: Not yet recruiting

Shoulder Health After Rehabilitation and Performance Training

The goal of this study is to investigate the impact of a home-based shoulder strength training on the overall shoulder health in manual wheelchair users, and if the timepoint of such a training makes a difference. The study is focusing on persons with a spinal cord injury in the thoracic or lumbar region of the spine, that have only recently been injured and will soon be discharged from primary rehabilitation. The shoulder training will take place either 3 or 12 months after discharge from primary rehabilitation and will be carried out twice a week for 12 weeks. There are six measurements occurring every three months, which leads to an overall duration of 15 months. The measurements consist of: * Questionnaires about independence in daily life, participation, quality of life and physical activity * Assessment of shoulder strength, range of motion and function * Measurement of the daily wheelchair use during one week via sensors that are fixed to the wheelchair and wrist * one further questionnaire at the end of the measurement week about the occurrence of shoulder pain Additionally, on four of the six measurement timepoints, a magnet resonance image (MRI) of the shoulder will be taken to assess the shoulder status (pathology, muscle volume and quality). Though all these measurements the researchers can additionally assess the load of daily life on the shoulders, and how well this matches the preparation during the primary rehabilitation.

Participants needed: 40
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Swiss Paraplegic Research, NottwilUpdated: Nov 24, 2025Locations: 1
Eligibility criteria

Persons with a paraplegia below T2 [+3]

Trauma or surgery of the shoulder with medical indication for immobilization of... [+5]

Status: Recruiting

Optimized Recovery After Trauma in Geriatric Patient

Currently, there is evidence that structured care within the healthcare system increases the conditions for good care and better recovery. We want to investigate whether a new care concept (gero-ERAT) that combines two variants of structured care can improve the recovery of elderly patients affected by a physical trauma. Our hope is that the project will reduce the complications, short care times, fewer re-admissions and that more patients can return to regular living, which reduces the suffering for the patient and his relatives. In addition to patient benefit, a successful outcome will also result in reduced costs for healthcare and society as a whole. The concept of care is based on an increased patient participation, which is in line with the values of the Västra Götaland region and the Sahlgrenska university hospital Through the PhD project, four studies will be published. A qualitative interview study to investigate patients' experiences of care and recovery after trauma. After that, a prospective cohort survey of two groups is carried out; conventional care and gero-ERAT. Data will begin to be collected in the control group and when the control group is full geroRATAT will be implemented in the care department and we then collect data in the intervention group. Based on collected data, we will publish two additional studies one with a focus on health economics as well as one focusing on care time and recovery based on age and harvest estimation.

Participants needed: 540
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Vastra Gotaland RegionUpdated: Nov 25, 2024Locations: 1
Eligibility criteria

≥ 65 years old [+2]

Documented palliative care [+1]