[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lewy-body-disease-with-mild-cognitive-impairment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lewy-body-disease-with-mild-cognitive-impairment":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100627475",false,"NCT07449117","Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases","Immediate Effects of Non-invasive Temporal Interference Stimulation Targeting Deep Fronto-Striatal Structures on Language Processing and Behavioral Performance in Patients With Neurodegenerative Diseases","Inclusion Criteria:\n\n* Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).\n\nExclusion Criteria:\n\n* Any severe psychiatric disorder.\n* History of other neurological diseases affecting the central nervous system.\n* Severe head trauma.\n* Uncompensated internal or oncological disease.\n* Presence of MRI-incompatible metal in the body (e.g., pacemaker).","ALL","60 Years","80 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.",[26,27,28],"Mild Cognitive Impairment (MCI) Amnestic","Lewy Body Disease With Mild Cognitive Impairment","Parkinson's Disease With Mild Cognitive Impairment",[30,31,32,33,34,35,36,37,38],"Temporal Interference Stimulation","Functional Magnetic Resonance Imaging","Sentence Comprehension","Language Processing","Brain Connectivity","Striatum","Fronto-striatal Circuit","Mild Cognitive Impairment","Neurodegenerative Diseases","RECRUITING","2026-02-27",{"date":42,"type":43},"2026-03-04","ACTUAL",{"date":45,"type":20},"2026-03",{"date":47,"type":20},"2028-12",{"name":49,"class":50},"Masaryk University","OTHER",""]