[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"limb-absence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:limb-absence":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100600923",false,"NCT07103798","Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators","Does a Microprocessor-Controlled Prosthetic Knee Joint Improve Mobility and Quality of Life in K2-Level Veteran Ambulators?","MPK-K2","Inclusion Criteria:\n\n* Unilateral, transfemoral amputation (any etiology).\n* Age from 45-85 years.\n* Residual limb length classified as standard (i.e., medium) to long.\n* Prosthesis user for at least 1 year prior to enrolling in the study.\n* K2-level classification while using their NMPK.\n* Good sensation on their residual limb.\n* Good skin integrity upon visual inspection.\n* Presents with good socket fit based upon a standard assessment by the study prosthetist.\n\nExclusion Criteria:\n\n* Bilateral leg amputations.\n* Individuals with a knee disarticulation.","ALL","45 Years","85 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and\u002For stance-phase control as appropriate for the prosthesis user during gait. The purpose of this proposed investigation is to determine if there are substantial physical and psychological benefits to fitting lower functioning Veteran ambulators having transfemoral amputations with an MPK compared with a nonmicroprocessor-controlled knee (NMPK). Using a repeated-measures, cross-sectional experimental design, approximately 20 Veterans with unilateral, transfemoral amputations will be evaluated on two separate occasions at the Jesse Brown VA Medical Center or the Edward Hines, Jr. VA Hospital, first with their conventional NMPK and then again after a 2-month accommodation period with the College Park Icon MPK.",[27,28,29],"Transfemoral Amputation","Limb Loss","Limb Absence",[31,32,33,34,35,36,37],"amputation","limb loss","limb deficiency","transfemoral","above-knee","prosthesis","knee joint","NOT_YET_RECRUITING","2026-05-07",{"date":41,"type":42},"2026-05-08","ACTUAL",{"date":44,"type":21},"2026-07-01",{"date":46,"type":21},"2028-06-30",{"name":48,"class":49},"VA Office of Research and Development","FED",{"id":51,"slug":4,"hasResults":10,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},"100532855","NCT06218238","A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation","Do Transfemoral Prostheses With Powered Prosthetic Knee Flexion and Extension Improve Mobility? A Biomechanical Evaluation of the Ossur Power Knee","OPKTFA","Inclusion Criteria:\n\n* Unilateral, transfemoral amputation (any etiology).\n* Age from 45-75 years.\n* Residual limb length classified as standard (i.e., medium) to long.\n* Prosthesis user for at least 1 year prior to enrolling in the study.\n* K3 or K4 level ambulator.\n* Good sensation on their residual limb(s) (upon routine clinical examination).\n* Good skin integrity upon visual inspection.\n* Does not require the use of assistive devices to walk for short distances.\n* Not currently taking medications that are known to affect balance or gait.\n* Presents with good socket fit based upon a standard assessment by the study prosthetist.\n\nExclusion Criteria:\n\n* Bilateral amputations\n* Individuals with a knee disarticulation","75 Years",{"count":20,"type":21},[24],"Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and\u002For stance-phase control as appropriate for the prosthesis user during gait. The Ossur Power Knee is the only commercially-available MPK that uses a motor to provide active power generation during walking and other activities. The purpose of this proposed investigation is to perform and compare biomechanical evaluations of the Power Knee and Ossur Rheo XC, a passive MPK, during walking and other activities by prosthesis users. Furthermore, mobility between male and female subjects will be compared to determine if there are differences in prosthetic knee usage on the basis of sex.",[27,28,29],[31,32,33,34,35,36,37],"RECRUITING","2025-09-08",{"date":66,"type":42},"2025-09-09",{"date":68,"type":42},"2024-04-01",{"date":70,"type":21},"2027-03-31",{"name":48,"class":49},1,""]