[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"long-term-oxygen-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:long-term-oxygen-therapy":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100608232",false,"NCT07198880","Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University Hospital","Inclusion Criteria:\n\n* Patients more than 18 year old.\n* Severe COPD (classified as GOLD stage Ⅲ and IV), confirmed by FEV₁\u002FFVC \\\u003C 70% and FEV₁ \\\u003C 50% of the predicted value. (9)\n* Persistent hypercapnia (PaCO₂ ≥ 60 mmHg ≥2 weeks after resolution of acute exacerbation and compliant on optimal medical therapy with or without long term oxygen therapy\n\nExclusion Criteria:\n\n* Other significant respiratory disorders (e.g,history suggestive OSA, Body Mass Index more than 30, pneumothorax, bullous lung disease, advanced interstitial lung diseases , restrictive thoracic wall diseases , neuromuscular disease).\n* Undergone intubation or tracheostomy prior to NIV initiation during the last 2 months.\n* Those using addictive narcotic medications.\n* Comorbidities and diseases that might confound survival outcomes (e.g., malignancy, advanced hepatic or renal diseases).\n* Pregnancy\n* Refusal or Inability to tolerate NIV during initiation and adaptation phase.\n* Expected Poor compliance (patients deemed unlikely to adhere to nightly NIV use such as no family support, severe frailty).\n* Withdrawal criteria: stopping bipap or medical treatment, voluntary withdrawal by the participant, failure to attend scheduled visits, and significant clinical deterioration requiring alternative management during the study period","ALL","18 Years","80 Years",{"count":18,"type":19},40,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study aims to evaluate the impact of long-term home non-invasive ventilation (NIV) on patients with COPD",[25,26,27,28,29,30,31],"COPD","COPD (Chronic Obstructive Pulmonary Disease)","Ventilation Therapy","Non Invasive Ventilation (NIV)","BiPAP","Hypercapnia","Long Term Oxygen Therapy","NOT_YET_RECRUITING","2025-09-27",{"date":35,"type":36},"2025-09-30","ACTUAL",{"date":38,"type":19},"2026-01-01",{"date":40,"type":19},"2028-01-01",{"name":42,"class":43},"Assiut University","OTHER",""]