[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lung-ground-glass-opacities\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lung-ground-glass-opacities":57},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100546369",false,"NCT06394037","Active Surveillance for Limited GGNs","Active Surveillance for Patients with Limited Ground-glass Nodules in China: a Prospective Multi-center Single-arm Trial (ECTOP-1028)","Patients eligible for enrollment in the study are required to meet all the following criteria.\n\n1. Demonstrates the following on thin-section computed tomography (TSCT) scan:\n\n   1. Presence of one or two GGNs (bilateral lesions are permitted).\n   2. All lesions have remained stable without regression or enlargement for at least 3 months.\n   3. The dominant lesion (the lesion with the largest maximum tumor diameter) has a maximum tumor diameter ≥0.6cm and ≤2cm.\n   4. CTR ≤0.25 in lesions.\n   5. No lymph node with a diameter \\>1cm in the mediastinal view.\n   6. Not adjacent to the pleura in dominant lesion and no sign of pleural retraction in any lesions.\n2. Has not previously undergo any anti-tumor drug or radiation therapy for the lung lesions.\n3. Aged 18-75 years.\n4. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n5. Written informed consent.\n\nPatients will be excluded if they meet any of the following criteria.\n\n1. History of any prior malignancies within the past 5 years.\n2. History of lung surgery.\n3. History of interstitial pneumonia, pulmonary fibrosis or other severe pulmonary diseases.\n4. Presence of severe or uncontrolled diseases that may possibly reduce the 10-year life expectancy.","ALL","18 Years","75 Years",{"count":19,"type":20},387,"ESTIMATED","10 Years","OBSERVATIONAL","This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) . The primary objective of the study is to assess the 5-year overall survival of patients with one or two ground-glass opacities by employing an active surveillance approach rather than immediate surgical resection.",[25,26],"Lung Ground-glass Opacities","Active Surveillance","NOT_YET_RECRUITING","2025-01-29",{"date":30,"type":31},"2025-01-31","ACTUAL",{"date":33,"type":20},"2025-05-01",{"date":35,"type":20},"2038-05-01",{"name":37,"class":38},"Fudan University","OTHER",1,{"id":41,"slug":4,"hasResults":10,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":46,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":48,"conditions":49,"keywords":4,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":51,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":39},"100523608","NCT06097910","Surveillance for Multifocal GGNs","Active Surveillance for Patients with Multifocal Ground-glass Nodules: a Prospective, Multi-center, Single-arm Trial (ECTOP-1021)","Inclusion criteria Patients eligible for enrollment in the study are required to meet all the following criteria.\n\n1. Demonstrates the following on thin-section computed tomography (TSCT) scan:\n\n   1. Presence of three or more GGNs (bilateral lesions are permitted).\n   2. All lesions have remained stable without regression or enlargement for at least 3 months.\n   3. The dominant lesion (the lesion with the largest maximum tumor diameter) has a maximum tumor diameter \\>=0.6cm and \\\u003C=2cm.\n   4. CTR \\\u003C=0.25 in all lesions.\n   5. No lymph node with a diameter \\>1cm in the mediastinal view.\n   6. Not adjacent to the pleura in dominant lesion and no sign of pleural retraction in any lesions.\n2. Aged 18-75 years.\n3. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n4. Has not previously undergo any anti-tumor drug or radiation therapy.\n5. Written informed consent.\n\nExclusion criteria Patients will be excluded if they meet any of the following criteria.\n\n1. History of any prior malignancies within the past 5 years.\n2. History of lung surgery.\n3. History of interstitial pneumonia, pulmonary fibrosis or other severe pulmonary diseases.\n4. Presence of severe or uncontrolled diseases that may possibly reduce the 10-year life expectancy.",{"count":47,"type":20},370,"This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) with the identification number ECTOP-1021. The primary objective of the study is to assess the overall survival of patients with multifocal ground-glass opacities by employing a active surveillance approach rather than opting for surgical resection.",[25,26],"RECRUITING",{"date":30,"type":31},{"date":53,"type":31},"2023-11-01",{"date":55,"type":20},"2036-11-01",{"name":37,"class":38},""]