[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"molar-fourth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:molar-fourth":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100551314",false,"NCT06458478","Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery","Effects of the Application of a Hyper-oxygenated Gel After Extraction of Impacted Lower Third Molars: Randomized Controlled Study","Inclusion Criteria:\n\n* good systemic and local health conditions of the patient;\n* age between 18 and 35 years;\n* understanding of the Italian language,\n* indications for the extraction of impacted bilateral lower third molars (38 and 48) according to the criteria reported in the classifications of Winter and that of Pell and Gregory;\n* the root of the impacted third molars is completely formed.\n\nExclusion Criteria:\n\n* diabetes mellitus;\n* systemic arterial hypertension;\n* hyperthyroidism;\n* osteoporosis;\n* immunosuppressed;\n* osteonecrosis of the jaws;\n* pregnancy;\n* patients with mandibular third molars in position C according to \"the Pell \\& Gregory Classification\" on the radiological measurements (angles and positions) for which third molar extraction surgery is required.;\n* local alterations such as pericoronitis, odontogenic cysts and tumors in relation to the third molars;\n* allergies;\n* ordinary use of analgesics or antibiotics by the patient.","ALL","18 Years","35 Years",{"count":19,"type":20},72,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to evaluate whether the topical application of Novox® Drop on surgical wounds after the extraction of lower third molars can have a clinical advantage.\n\nThe primary objective of the study is to evaluate the possible reduction of masseteric trismus (masticatory muscle spasm - primary outcome) and of post-operative pain and facial edema (swelling - secondary outcomes) after the extraction of impacted third molars compared to those who do not use it (placebo=glycerin-based gel).",[26,27,28,29,30],"Molar, Fourth","Extracting Own Teeth","Edema Face","Pain","Trismus",[32,33,34,35,36,37],"dysodontiasis","third molar","oral surgery","edema","trismus","pain","RECRUITING","2024-06-12",{"date":41,"type":42},"2024-06-13","ACTUAL",{"date":44,"type":20},"2024-07-01",{"date":46,"type":20},"2025-02-01",{"name":48,"class":49},"Azienda Ospedaliera di Perugia","OTHER",""]