[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nebulized-dexmedetomidine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nebulized-dexmedetomidine":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100619522",false,"NCT07345715","Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy","Comparison Between Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy: A Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n* Children aged between 3 and 7 years.\n* Both sexes.\n* Classified as American Society of Anesthesiologists (ASA) physical status I or II according to the American Society of Anesthesiologists.\n* Scheduled for elective adenotonsillectomy under general anesthesia.\n\nExclusion Criteria:\n\n* Parental refusal to participate in the study.\n* Known allergy or hypersensitivity to dexmedetomidine, melatonin or midazolam.\n* Presence of developmental delay.\n* Central nervous system disorders.\n* Intellectual disability (formerly termed mental retardation).\n* Neurological or psychiatric conditions associated with anxiety or agitation (e.g., cerebral palsy, epilepsy, separation anxiety disorder, attention-deficit\u002Fhyperactivity disorder).\n* Current or recent treatment with anticonvulsants or sedative medications","ALL","3 Years","7 Years",{"count":19,"type":20},96,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to compare the efficacy of using oral Melatonin versus nebulized Dexmedetomidine in limitation of emergence agitation in children undergoing adenotonsillectomy.",[26,27,28,29,30],"Oral Melatonin","Nebulized Dexmedetomidine","Emergence Agitation","Children","Adenotonsillectomy","RECRUITING","2026-01-07",{"date":34,"type":35},"2026-01-16","ACTUAL",{"date":37,"type":35},"2025-07-01",{"date":39,"type":20},"2027-07-01",{"name":41,"class":42},"Tanta University","OTHER",""]