[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neutrophil-mediated-inflammatory-dermatoses\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neutrophil-mediated-inflammatory-dermatoses":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100495575",false,"NCT05732987","Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases","Case-Control Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases","NEUTROSKIN","Inclusion Criteria:\n\n* written consent of the participating person\n* diagnosis of a disease in the NMID form group or proband of the control group\n\nExclusion Criteria for patients:\n\n* Missing informed consent if samples collected after 2014\n* no diagnosis of NMID\n\nExclusion Criteria for healthy controls:\n\n* Missing informed consent",true,"ALL","18 Years","100 Years",{"count":21,"type":22},3370,"ESTIMATED","OBSERVATIONAL","This study is to identify rare, disease-causing mutations of several rare neutrophil dermatoses. To identify associations between NMID and variants in the genome next generation sequencing, mainly whole exome sequencing, will be used. In a second approach the expression level of already known inflammatory proteins in skin samples will be investigated.",[26,27],"Neutrophil-mediated Inflammatory Dermatoses","Inflammatory Dermatoses",[29,30,31,32],"inflammasome","inflammation-driving pathway","gene variants","next generation sequencing","RECRUITING","2023-08-21",{"date":36,"type":37},"2023-08-22","ACTUAL",{"date":39,"type":37},"2023-02-03",{"date":41,"type":22},"2029-09",{"name":43,"class":44},"University Hospital, Basel, Switzerland","OTHER",""]