Non Hodgkin Lymphoma Refractory Relapsed

5

Review clinical trials related to Non Hodgkin Lymphoma Refractory Relapsed. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

This Phase 3 study compares rondecabtagene autoleucel (ronde-cel), a dual-targeting CD19/CD20 CAR T-cell therapy, with investigator's choice of CD19 CAR T-cell therapy in patients with relapsed or refractory large B-cell lymphoma in the second-line setting.

Participants needed: 400
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Lyell Immunopharma, Inc.Updated: Jun 8, 2026Locations: 38
Eligibility criteria

CAR T cell naïve and eligible to receive a CD19 CART-cell therapy [+11]

Patients ineligible to receive CD19 CAR T-cell therapy [+5]

Status: Recruiting

Study for Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma

Open Label, Phase 1 study of CD19 t-haNK as a single agent and combination with rituximab in subjects with selected CD19+ and CD20+ R/R B-cell non-Hodgkin Lymphoma( NHL).

Participants needed: 10
Trial details
Phase: Phase 1Age: 18-99Biological sex: AllType: InterventionalSponsor: ImmunityBio, Inc.Updated: May 4, 2026Locations: 3
Eligibility criteria

Age ≥ 18 years old. [+10]

Histologically documented primary CNS lymphoma, CLL, Burkitt, or Burkitt-like ly... [+27]

Status: Recruiting

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

This study is a first-in-human (FIH), Phase 1, multicenter, open-label study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and evaluate the preliminary anti-tumor activity of LTZ-301 administered as a single agent in adult subjects with relapsed or refractory B-cell non-Hodgkin lymphoma

Participants needed: 42
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: LTZ Therapeutics, Inc.Updated: Feb 10, 2026Locations: 5
Eligibility criteria

Age ≥ 18 years [+4]

CLL, or Richters transformation [+10]

Status: Recruiting

Amping up With PemJAK

The purpose of this study is to understand and determine if ruxolitinib added to pembrolizumab is safe and effective for the treatment of relapsed or refractory Hodgkin and non-Hodgkin lymphomas.

Participants needed: 53
Trial details
Phase: Phase 2Age: 18-95Biological sex: AllType: InterventionalSponsor: Seda S. ToluUpdated: Dec 16, 2025Locations: 1
Eligibility criteria

Arm 1: PTCL [+41]

1) Diagnosis of Adult T-Cell Leukemia/Lymphoma (ATLL) [+17]

Status: Recruiting

Study of CART Cell (MB-CART19.1) in Patients With Relapsed or Refractory CD19 Positive NHL

This is a Prospective Single Center, open label, Non-randomized, Single Arm, Single Dose, Phase II Clinical Trial. Adult patients \>18-year-old with CD19+ Non-Hodgkin lymphoma are eligible for the study if they meet eligibility criteria. Patients will receive a fresh single dose of MB-CART-19.1 and will be followed for 12 months and evaluated for efficacy and safety.

Participants needed: 26
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: King Hussein Cancer CenterUpdated: Dec 9, 2025Locations: 1
Eligibility criteria

Patients after progression on at least one standard chemotherapy and one salvage... [+10]

Residual CNS disease [+15]