[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-verbal-communication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-verbal-communication":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100625981",false,"NCT07429695","Eye-Tracking Interactive Agent in Non-verbal ICU Patients","Eye-Tracking Interactive Agent in Non-verbal ICU Patients: A Study Protocol of a Randomized Controlled Trial With an Embedded Qualitative Study","Inclusion Criteria:\n\n* Aged ≥ 18 years\n* Patients in the ICU who are unable to communicate through normal verbal means due to endotracheal intubation\u002Ftracheotomy, muscle or nerve injury, acute\u002Fchronic spinal cord injury, etc.\n* Richmond Agitation-Sedation Scale (RASS) score of -1 to 1\n* Primary caregivers are adults\n* Able to read Chinese characters and follow simple commands\n* Willing to participate in this study.\n\nExclusion Criteria:\n\n* Diseases associated with cognitive impairment, such as pulmonary encephalopathy, hepatic encephalopathy, diabetic hyperosmolar coma, and coma of unknown cause\n* A history of mental disorders, dementia or pre-dementia, or intellectual disability\n* Conditions precluding cooperation with eye-tracking interaction, such as blindness or inability to elevate the eyelids.","ALL","18 Years",{"count":18,"type":19},54,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to determine whether an eye-tracking interactive agent can ameliorate communication impairments and reduce the incidence of complications among non-verbal patients in the intensive care unit (ICU). The main questions it aims to answer are:\n\nDoes the eye tracking interactive agent alleviate communication impairments among non-verbal patients in the ICU? Does the eye tracking interactive agent improve communication efficiency among non-verbal patients in the ICU? Does the eye tracking interactive agent m reduce the incidence of negative emotions among non-verbal patients in the ICU? Does the eye tracking interactive agent shorten the ICU length of stay for non-verbal patients in the ICU? Does the eye tracking interactive agent reduce the dosage of analgesic and sedative medications for non-verbal patients in the ICU? Does the eye tracking interactive agent improve family satisfaction for non-verbal patients in the ICU? Does the eye tracking interactive agent alleviate nurses' communication burden among non-verbal patients in the ICU? Researchers will compare eye tracking interactive agent to conventional techniques to see if e eye tracking interactive agent works to alleviate communication impairments.\n\nParticipants will:\n\nUse an eye tracking interactive agent for augmentative communication for 2 consecutive days Document each communication's details, ICU LOS, and analgesic-sedative dosages; assess communication difficulty severity, delirium, anxiety, family satisfaction and nurses' communication burden with validated scales.",[25,26,27,28],"Eye Tracking","ICU","Communication Barriers","Non-Verbal Communication","NOT_YET_RECRUITING","2026-02-22",{"date":32,"type":33},"2026-02-24","ACTUAL",{"date":35,"type":19},"2026-04-01",{"date":37,"type":19},"2027-12-31",{"name":39,"class":40},"Shanghai Zhongshan Hospital","OTHER",""]