[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oropharyngeal-neoplasms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oropharyngeal-neoplasms":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100565449",false,"NCT06642324","Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas","Exploration of Human Papillomavirus Association and Genomic Characteristics in Head and Neck Squamous Cell Carcinomas in Bangladesh","HPV & HNSCC","Inclusion Criteria:\n\n1. Patient Age: adult (\\> 18 years)\n2. Head and neck squamous cell carcinoma diagnosed by biopsy (Histopathology confirmed HNSCC).\n3. Diagnosed cases specific Head-Neck sub-sites: (oral cavity, oropharynx, hypopharynx, larynx, tongue)\n4. Patient's Consent\n\nExclusion Criteria:\n\n1. Patient Age: children (\\\u003C 18 years)\n2. Cancers of any part of the body other than the head-neck region.\n3. People without HNSCC\n4. Any chronic diseases, genetic diseases, acute\u002Fchronic infectious diseases, etc. -",true,"ALL","18 Years",{"count":20,"type":21},550,"ESTIMATED","OBSERVATIONAL","Head and neck squamous cell carcinoma (HNSCC) represents a significant public health burden in Bangladesh with a high incidence and mortality rate. While traditional risk factors like tobacco and betel nut chewing contribute to HNSCC incidence, the emergence of HPV-associated HNSCC presents a unique challenge. The main goal of this observational study is to explore the prevalence, risk factors, and biological mechanisms underlying food habits and HPV-driven HNSCC in the population and identify the genomic changes and characteristics related to this malignancy. This study will provide the prevalence of HPV-associated HNSCC and screening the HPV typing in the Bangladeshi population, identify risk factors, and any biologically driven mechanisms causing HNSCC.",[25,26],"Head Neck Cancer","Oropharyngeal Neoplasms","RECRUITING","2024-12-28",{"date":30,"type":31},"2024-12-31","ACTUAL",{"date":33,"type":31},"2024-04-30",{"date":35,"type":21},"2025-09-30",{"name":37,"class":38},"Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh","OTHER",""]