Pathological Conditions Signs And Symptoms

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Review clinical trials related to Pathological Conditions Signs And Symptoms. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

The objective of this study is to assess the safety and efficacy of the Freesolve resorbable magnesium scaffold (RMS) in the treatment of subjects with up to two de novo lesions in native coronary arteries compared to the Xience coronary drug-eluting stent (DES) system

Participants needed: 1,859
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: TeleflexUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Subject is ≥ 18 years and ≤ 80 years of age [+5]

Subject is hemodynamically stable with documented declining cardiac biomarkers; [+35]

Status: Recruiting

Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH

This registry study aims to confirm that FETO increases neonatal survival to discharge and reduces long-term morbidity in fetuses with isolated left CDH and o/e LHR \< 30%, or isolated right CDH and o/e LHR ≤ 45%, compared to those receiving standard care. This prospective registry plans to enroll 80 pregnant women (40 treatment/40 control) with fetuses diagnosed with isolated CDH, and the children will be followed for up to 24 months.

Participants needed: 80
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Apr 23, 2026Locations: 1
Eligibility criteria

Pregnant women age 18 years and older [+8]

Patient < 18 years of age [+16]

Status: Not yet recruiting

Hypersensitivity to Amylin in Post-Traumatic Headache

Pramlintide is a peptide analogue of human amylin which is a vasoactive substance involved in the pathogenesis of headache. This study investigates whether pramlintide induces migraine-like headache in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).

Participants needed: 21
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Danish Headache CenterUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Age 18 to 65 years of age upon entry into screening [+3]

> 1 mild traumatic injury to the head [+14]

Status: Not yet recruiting

Amylin-Induced Migraine Attacks Without Aura

Pramlintide is a peptide analogue of human amylin which is a vasoactive signaling molecule involved in the pathogenesis of migraine. This study investigates whether pramlintide induces migraine attacks without aura in people with migraine without aura.

Participants needed: 21
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Danish Headache CenterUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Age 18 to 65 years of age upon entry into screening [+4]

Any history of a primary or secondary headache disorder other than migraine with... [+16]