[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peritonsillar-cellulitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peritonsillar-cellulitis":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100638307",false,"NCT07577232","Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar Abscess","Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar Abscess - Proposal for a Multicenter Cluster Randomized Trial","Inclusion Criteria:\n\n* Patients referred to the ENT outpatient clinic with a suspected PTA.\n* 18 years of age or older.\n\nExclusion Criteria:\n\n* Unable to understand the verbal information, participating in research.\n* Prior surgical interventions (needle aspiration, surgery, incision) during the course of the disease.\n* Compromised airways, needing acute airway management.","ALL","18 Years",{"count":18,"type":19},368,"ESTIMATED","INTERVENTIONAL",[22],"NA","Peritonsillar abscess (PTA) is a collection of pus between the palatine tonsil and the constrictor muscle. PTA is detected by recognizing characteristics during clinical examination: redness, pain, malaise, trismus, and unilateral peritonsillar swelling. Clinical assessment, including inspection and palpation, is the traditional diagnostic method for patients suspected of having PTA. If PTA is suspected, aspiration with a large-gauge needle or incision is performed to drain the abscess . It can be challenging to distinguish PTA and peritonsillar cellulitis (PTC) based on clinical examination alone. Due to the increased availability of point-of-care ultrasound, it is a part of the diagnostic workup of PTA. Several studies have shown that transoral US can improve the diagnostic accuracy of patients with a suspected PTA. However, no large multicenter study has evaluated whether one of these methods is superior to the other. It is therefore very clinician-dependent whether the patient will have a transoral US performed or not. The investigators hypothesize that transoral US will increase the diagnostic accuracy of PTA compared to solely clinical examination, which is a visual and palpatory assessment. This will result in fewer unnecessary aspiration attempts and overlooked PTAs. Additionally, the investigators wish to investigate the number of aspirations of transoral US-guided needle aspirations compared to aspirations without ultrasound.\n\nMethods This is a cluster randomized study. Patients with suspected PTA will be randomized 1:1 to groups A and B. The cluster randomization will happen weekly using an online randomization tool.\n\nParticipants are patients refeered to the outpatient clinic on suspicion of a peritonsillar absces.\n\nThe primary outcome is the diagnostic accuracy\n\nThe investigators aim to determine whether transoral US is a standard part of the clinical examination by comparing clinical examinations with and without US.",[25,26,27],"Peritonsillar Abscess","Peritonsillar Cellulitis","Tonsillitis",[29,30,31],"Transoral ultrasound","peritonsillar abscess","Peritonsillar cellulitis","RECRUITING","2026-05-05",{"date":35,"type":36},"2026-05-11","ACTUAL",{"date":38,"type":36},"2025-06-09",{"date":40,"type":19},"2026-07-01",{"name":42,"class":43},"Rigshospitalet, Denmark","OTHER",3,""]