[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"preterm-intraventricular-hemorrhage\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:preterm-intraventricular-hemorrhage":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100476917",false,"NCT05490173","The Pilot Experimental Study of the Neuroprotective Effects of Exosomes in Extremely Low Birth Weight Infants","Inclusion Criteria:\n\n• Premature newborns of gestational age (GA) 25\u002F0-27\u002F6 weeks,\n\nExclusion Criteria:\n\n* Missing written parental consent\n* Damages to the nasal mucosa\n* Maxillofacial defects\n* Major congenital anomalies (including chromosomal aberrations, cyanotic congenital heart defects, syndromes likely affecting long-term outcome, and major congenital malformations requiring surgical correction during newborn period)\n* Infants who died before 48 hours, infants in whom the clinical decision to withhold intensive care was made, infants who were not considered viable\n* Infants with edematous hemolytic disease of newborns, non-immune fetal dropsy,\n* Multifetal Gestations\n* Participation in another study with ongoing use of an unlicensed investigational product from 28 days before study enrollment until the end of the study","ALL","1 Day","3 Days",{"count":18,"type":19},10,"ESTIMATED","INTERVENTIONAL",[22],"NA","To study the safety and efficacy of intranasal administration of exosomes derived from mesenchymal stromal cells on long-term neurodevelopmental outcome in extremely low birth weight infants born at gestational age 25\u002F0-27\u002F6 weeks.",[25,26,27,28,29],"Premature Birth","Extreme Prematurity","Preterm Intraventricular Hemorrhage","Hypoxia-Ischemia, Cerebral","Neurodevelopmental Disorders",[31],"Extremely low birth weight, neuroprotection","NOT_YET_RECRUITING","2022-09-26",{"date":35,"type":36},"2022-09-28","ACTUAL",{"date":38,"type":19},"2022-10-05",{"date":40,"type":19},"2026-12-28",{"name":42,"class":43},"Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare","OTHER_GOV",""]