[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"protein-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:protein-disease":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100424263",false,"NCT04804618","Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease","Exploring Research on Early Warning Indicators of Protein in Patients With Mild Cognitive Impairment and Alzheimer's Disease","Inclusion Criteria:\n\n1. Older than 55-year-old，male or female.\n2. patients meet the diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease(AD) or whose family members were diagnoed with AD\n3. Complete self-rating scale for memory impairment (AD-8 scale)\n4. Those who agree to participate in clinical research and sign informed consent.\n\nExclusion Criteria:\n\n1. Patients with acute cardiovascular and cerebrovascular diseases, acute infections (pneumonia, urinary tract infection, oral infection, digestive tract infection), severe renal dysfunction, and uremia;\n2. Pregnant or lactating women;",true,"ALL","55 Years",{"count":19,"type":20},650,"ESTIMATED","OBSERVATIONAL","This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use liquid chromatography\u002Fmass spectrometry (LC-MS\u002FMS) technology to explore early warning indicators of protein in patients with mild cognitive impairment and Alzheimer's disease",[24,25],"Alzheimer Disease, Early Onset","Protein; Disease",[27,28,29],"Alzheimer Disease","biomarker","protein","RECRUITING","2022-11-14",{"date":33,"type":34},"2022-11-15","ACTUAL",{"date":36,"type":34},"2021-06-01",{"date":38,"type":20},"2026-06-30",{"name":40,"class":41},"Guangzhou University of Traditional Chinese Medicine","OTHER",""]