[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"proximal-dental-caries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:proximal-dental-caries":86},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100642802",false,"NCT07648485","Clinical Performance of CAD\u002FCAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities","Clinical Performance of CAD\u002FCAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities: Two-Year Randomized Clinical Trial","Inclusion Criteria:\n\n* Systematically healthy male or female subjects aged 16 to 50 years.\n* Patients with good oral hygiene.\n* Presence of a single vital molar with coronal destruction due to caries, defined as radiographic evidence of caries involving more than 50% of the total dentin thickness with loss of at least one proximal wall.\n* Cavitary preparation involving loss of at least one proximal walls (mesial and\u002For distal), with intact buccal and lingual walls, and all cavosurface margins located in enamel.\n* Presence of functional opposing teeth in stable occlusion\n\nExclusion Criteria:\n\n* Presence of systemic diseases (e.g., uncontrolled diabetes, immune disorders).\n* Current pregnancy or lactation.\n* Documented allergy to resin-based composites or adhesive systems.\n* Evidence of pulpal necrosis or previous endodontic treatment in the target tooth.\n* Presence of cracks or fractures involving the tooth structure.\n* Active localized or generalized periodontal disease.\n* Evidence of parafunctional habits, including bruxism or clenching.\n* High caries risk.","ALL","16 Years","50 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","this study aims to compare the clinical performance of hard hybrid ceramics and composite resin indirect restorations fabricated by CAD\u002FCAM technology for the vital teeth with occluso-proximal cavities. the clinical performance assessed include marginal adaptation primarily and in addition to Color match, marginal discoloration, aesthetic anatomic form, recurrent caries and restoration fracture and post-operative hypersensitivity. the clinical performance will be assessed after the restoration cementation, after 6, 12, 18 and 24 months.",[26,27,28],"Dental Caries","Cavity, Dental","Proximal Dental Caries",[30,31,32,33,34],"indirect restoration","CAD\u002FCAM","clinical performance","inlay","hybrid ceramics","NOT_YET_RECRUITING","2026-06-13",{"date":38,"type":39},"2026-06-16","ACTUAL",{"date":41,"type":20},"2026-08",{"date":43,"type":20},"2028-11",{"name":45,"class":46},"Cairo University","OTHER",{"id":48,"slug":4,"hasResults":10,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":15,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":66,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":5},"100596108","NCT07041164","Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years","NILT","Inclusion Criteria:\n\n* Healthy Children aged 4-10 years\n* Low risk for periodontal disease\n* At least one quadrant contains fully erupted, well-aligned adjacent primary molars that are free of restorations, exhibit no clinically visible cavitated caries, demonstrate tooth mobility of grade 2 or less, show no developmental dental anomalies\n* Bitewing radiographs show at least one radiolucent lesion in the proximal surface of a primary molar classified as RA2 or RA3 according to the ICDAS II radiographic criteria\n\nExclusion Criteria:\n\n* Root resorption exceeding two-thirds of the root length\n* Demonstrate Frankl's behavior rating scale of 1 during either near-infrared light transillumination examination or tooth separation",true,"4 Years","10 Years",{"count":57,"type":20},174,"OBSERVATIONAL","The goal of this observational study is to compare the diagnostic performance of three detection methods for approximal carious lesions in primary molars among pediatric patients aged 4-10 years. The study focuses on children in three age groups: 4-6 years, 6-8 years, and 8-10 years. The main questions it aims to answer are:\n\n* Are the sensitivity, specificity, accuracy, and area under the curve (AUC) different across the three diagnostic techniques (bitewing radiography, near-infrared light transillumination, and their combination)?\n* Are these diagnostic parameters influenced by patient age?\n* Which technique yields the highest level of patient acceptance?\n\nResearchers will compare the three diagnostic approaches to determine whether age influences diagnostic performance and patient acceptance.\n\nParticipants will:\n\n* Be examined using bitewing radiography and near-infrared light transillumination\n* Undergo tooth separation for 7 days using orthodontic elastic separators\n* Receive clinical examination of the target approximal surface\n* Be asked to rate their experience using the Simplified Facial Pain Scale (S-FPS)",[61,62,63,64,28,65],"Dental Caries (Diagnosis)","Diagnostic Imaging","Optical Imaging","Radiographic Image Interpretation, Computer-Assisted","Tooth, Deciduous",[67,68,69,70,71,72,73,74,75],"proximal caries","primary molars","Pediatric Patients","Bitewing Radiography","Near-Infrared Light Transillumination","DIAGNOcam","clinical cavitation","children acceptance","Diagnostic accuracy","RECRUITING","2025-09-23",{"date":79,"type":39},"2025-09-29",{"date":81,"type":39},"2025-08-01",{"date":83,"type":20},"2026-04-30",{"name":85,"class":46},"Sawanya Prutthithaworn",""]