[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"second-degree-burn\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:second-degree-burn":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100627830",false,"NCT07453732","Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.","Pilot Study of Banana Leaves as a Primary Wound Dressing for Partial Thickness Burn Wounds","Inclusion Criteria:\n\n* \\\u003C10% Total body surface area (TBSA) partial thickness burns\n* Patients age 18 to 99\n* Primary admission (inpatient) to the UCHealth Burn and Frostbite Center\n* Burns \\\u003C48 hours old on admission\n\nExclusion Criteria:\n\n* Patients \\\u003C18 years\n* Patients who are pregnant, incarcerated, or cognitively impaired\n* Burns \\>48 hours old on admission\n* Patients with concurrent traumatic injuries\n* Patients with chemical, electrical, or friction burns\n* Full thickness burns\n* Burns to sensitive areas: face, genitals, hands, feet\n* Burns with evidence of infection on admission\n* Patients with a known allergy to bananas or latex\n* Patients with opioid use disorder or methamphetamine use disorder","ALL","18 Years","99 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients",[26,27,28],"Partial-thickness Burn","Pain","Second Degree Burn","NOT_YET_RECRUITING","2026-03-19",{"date":32,"type":33},"2026-03-24","ACTUAL",{"date":35,"type":20},"2026-04-01",{"date":37,"type":20},"2027-04-30",{"name":39,"class":40},"University of Colorado, Denver","OTHER",1,{"id":43,"slug":4,"hasResults":10,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":49,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":41},"100561920","NCT06596434","4-Aminopyridine to Treat Skin Burns","Inclusion Criteria:\n\n* Injured (burned) adults with a maximum severity of second-degree burns.\n* Burns involving at least 6cm2 of skin area\n* Acute burns within 7 days of injury\n* Cognitive ability to evaluate burn healing, report sensory and motor deficit during examination.\n* Adults aged 18-80\n* Ability to give written informed consent.\n* Capable of safely coming in for follow up visits on all scheduled appointments.\n\nExclusion Criteria:\n\n* History of multiple sclerosis, stroke or any other diagnosed neurological disorder\n* History of hypersensitivity to AMPYRA® or 4-aminopyridine\n* Current use of aminopyridine medications, including other compounded 4-AP\n* Suspected renal impairment based on the Choyke questionnaire.\n* History of difficult compliance with timely follow up\n* Patients outside the age range\n* Unable to provide informed consent.\n* Patients with a known history of a seizure disorder (4-AP overdose can, in selected cases, result in limited seizure activity).\n* Patients with a concomitant traumatic brain injury.\n* Patients unable to communicate.\n* Patients unwilling to complete the study requirements.\n* Patients currently taking organic cat-ion transporter 2 (OCT2) inhibitors, e.g. Cimetidine.\n* Pregnancy, breastfeeding or incarcerated individuals.\n* Non-English speaking\n* Patients unable or unwilling to take calibrated (with gauge) photographs of their wounds",{"count":48,"type":20},200,[50],"PHASE2","Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin. There is a need to develop treatments to accelerate and improve healing of burn injuries. More research is needed to evaluate the role of 4-AP, a promising new agent with an excellent safety profile, on wound and burn healing. The investigational treatment will be used to test the hypothesis that 4-AP accelerates burn healing in traumatically burned patients.",[53,28,54],"Burns","Wounds and Injuries",[56,57,53,58,59],"4-aminopyridine","4-AP","Second degree burn","Wounds","RECRUITING","2026-03-04",{"date":63,"type":33},"2026-03-05",{"date":65,"type":33},"2026-01-01",{"date":67,"type":20},"2028-09",{"name":69,"class":40},"John Elfar",""]