[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"targeted-axillary-dissection-tad\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:targeted-axillary-dissection-tad":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100614371",false,"NCT07278726","Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement","Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement: the UTAD Study of the Italian National Association of Breast Surgeons (ANISC)","UTAD","Inclusion Criteria:\n\n* Diagnosis of T0-T1-T2 ER+\u002FPR+ HER2- breast cancer with limited nodal involvement (1 or 2 suspicious lymph node on US, with at least 1 nodal positive cytology\u002Fhistology)\n* M0\n* Conservative surgery or mastectomy\n* Neoadjuvant treatment not recommended after a multidisciplinary discussion\n* Patients between 18 and 90 years old\n* Patients willing and able to follow the study procedures and available for follow-up over the entire duration of the study\n\nExclusion Criteria:\n\n* Psychiatric, addictive or any disorder, which compromises ability to give informed consent for participation in the study\n* Personal history of invasive breast cancer\n* Other invasive malignancies diagnosed in the last five years\n* Any condition that may expose the individual to a higher risk or preclude the study from achieving full compliance or completion\n* Contraindications to radiation therapy","ALL","18 Years","90 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","The present study aims to avoid axillary lymph node dissection (ALND) in patients with an Ultrasound (US) detected positive preoperative lymph node involvement (1 or 2 suspicious lymph-nodes) and a needle histology\u002Fcytology placing a marker in the most suspicious node undergoing upfront surgery if neoadjuvant treatment is not indicated. The marked lymph node will be retrieved along with sentinel lymphnode(SLN)(s) to minimize the false-negative rate and only in case of ≥3 positive SLNs ALND will be performed, in order to minimize surgical overtreatment among women with preoperatively confirmed axillary nodal metastasis.",[25,26,27],"ALND","Sentinel Lymph Node Biopsy (SLNB)","Targeted Axillary Dissection (TAD)","RECRUITING","2026-06-15",{"date":31,"type":32},"2026-06-16","ACTUAL",{"date":34,"type":32},"2026-01-28",{"date":36,"type":21},"2033-11",{"name":38,"class":39},"European Institute of Oncology","OTHER",14,""]