[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-extremity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-extremity":316},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,41,72,100,142,177,205,234,261,291],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100641349",false,"NCT07656922","Scapular Muscle Activation and Shoulder Performance in Migraine","INVESTIGATION OF SCAPULAR MUSCLE ACTIVATION AND SHOULDER PERFORMANCE IN INDIVIDUALS WITH MIGRAINE","Inclusion Criteria:\n\n* Aged 18-55 years\n* Diagnosed with migraine by a neurologist according to the ICHD-3 criteria\n* Experiencing at least 3 migraine attacks per month\n* Willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Presence of other types of headache disorders\n* History of trauma, fracture, or surgery involving the cranio-cervical region, scapular region, or upper extremity\n* Presence of neurological or inflammatory rheumatic diseases\n* Presence of psychiatric disorders\n* Receiving physiotherapy or rehabilitation for migraine or the cervical, thoracic, or upper extremity regions within the past 6 months\n* Cognitive impairment affecting the understanding of test instructions",true,"ALL","18 Years","55 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","Migraine is a significant health problem due to its high prevalence and substantial contribution to disability. Individuals with migraine have been reported to exhibit myofascial trigger points, increased pain sensitivity, and altered muscle activation patterns, particularly in the trapezius muscles. As the upper and middle trapezius muscles play critical roles in scapular stability and movement, alterations in these muscles may affect scapular orientation and upper extremity function. However, studies investigating the relationship between trapezius muscle activation, scapular orientation, and upper extremity performance in individuals with migraine are limited. Therefore, this study aimed to compare trapezius muscle activation, scapular orientation, and upper extremity performance between individuals with and without migraine. We hypothesized that individuals with migraine would exhibit altered upper and middle trapezius muscle activation, impaired scapular orientation, and reduced upper extremity performance compared with healthy controls.",[25,26,27],"Migraine","Upper Extremity","Muscle Activity","RECRUITING","2026-06-15",{"date":31,"type":32},"2026-06-18","ACTUAL",{"date":34,"type":32},"2026-04-01",{"date":36,"type":21},"2026-07-15",{"name":38,"class":39},"Ankara Yildirim Beyazıt University","OTHER",1,{"id":42,"slug":4,"hasResults":10,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":46,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":49,"conditions":50,"keywords":56,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":40},"100617479","NCT07319156","Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Presence of radicular pain diagnosed through clinical examination and cervical -MRI imaging Patients with cervical MRI findings demonstrating cervical disc herniation at least at one level consistent with their symptoms\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* History of cervical physical therapy within the past year\n* Symptoms or diagnosis of upper-extremity entrapment neuropathy\n* Patients with documented vitamin B12 or vitamin D deficiency within the last 2 years in available medical records\n* History of cervical surgery or cervical trauma\n* History of upper-extremity surgery or trauma\n* Individuals with intellectual disability\n* Presence of major psychiatric comorbidity\n* Diagnosis of polyneuropathy\n* Diagnosis of Diabetes Mellitus\n* Diagnosis of fibromyalgia\n* Use of medications that may impair proprioception\n* Pregnancy\n* Refusal to provide informed consent","65 Years",{"count":48,"type":21},58,"There is no study in the current literature that systematically investigates the extent of upper-extremity proprioceptive impairment in patients with radicular neuropathic symptoms secondary to cervical disc herniation, nor its association with clinical findings. Although existing reviews emphasize proprioceptive deficits in populations with neck pain or cervical spondylosis, no studies specifically address the subgroup of cervical disc-related radiculopathy. This gap in knowledge hinders the integration of proprioceptive assessments with upper-extremity functional outcome measures in diagnostic and rehabilitative processes, suggesting a need for more specific data to guide sensory-motor training approaches. The primary aim of the present study is to assess upper-extremity proprioception in patients with cervical radiculopathy by comparing them with a healthy control group. The secondary aim is to examine the relationship between upper-extremity proprioception and clinical outcomes, including parameters such as pain and functional status.",[51,52,53,54,55,26],"Cervical Radiculopathy","Proprioception","Cervical Disc Herniation","Proprioception Reaching Test","Pro-reach",[57,58,59,60,61,62],"cervical radiculopathy","proprioception","cervical disc herniation","proprioception reaching test","pro-reach","upper extremity","2026-06-02",{"date":65,"type":32},"2026-06-04",{"date":67,"type":32},"2025-12-20",{"date":69,"type":21},"2026-12-20",{"name":71,"class":39},"Marmara University",{"id":73,"slug":4,"hasResults":10,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":77,"enrollmentInfo":78,"targetDuration":80,"studyType":22,"phases":4,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":96,"leadSponsor":98,"locationsCount":40},"100640763","NCT07579676","DEVELOPMENT AND PSYCHOMETRIC EVALUATION OF THE NEUROCOGNITIVE UPPER EXTREMITY TESTS: A RELIABILITY AND VALIDITY STUDY","Inclusion Criteria\n\nGeneral Inclusion Criteria (Both Groups):\n\n* Individuals between the ages of 18 and 40\n* No passive range of motion limitations in the shoulder joint\n* Classified as healthy with no history of injury in the past year according to the Extended Nordic Musculoskeletal Questionnaire\n* Volunteered to participate in the study\\[cite: 1\\].\n\nAthlete Group Specific Criteria:\n\n* Physically active individuals\n* Currently active in sports clubs in Ankara and\u002For applied to the Hacettepe University Department of Sports Physiotherapy and Rehabilitation\n* History of training or physical activity at least three times a week for the past year\n* Participation in recreational or competitive above or below shoulder height sports\n\nControl Group Specific Criteria:\n\n* Healthy individuals who have applied to the Hacettepe University Department of Sports Physiotherapy and Rehabilitation Unit\n* Does not engage in regular physical activity\n* History of training or physical activity fewer than three times a week over the past year\n* No participation in recreational or competitive sports\n\nExclusion Criteria\n\n* Presence of symptomatic upper extremity pathology\n* History of upper extremity and\u002For trunk injury or surgery in the last 12 months\n* History of ongoing neck pain, neurological symptoms in any extremity, or back, hip, or knee pain in the last 12 months\n* Presence of a health condition that could cause a decrease in shoulder strength, such as inflammatory arthritis or neurological disorders\n* Presence of any systemic disease\n* Presence of visual or hearing impairments","40 Years",{"count":79,"type":21},30,"1 Week","The goal of this observational study is to develop an upper extremity neurocognitive performance test battery, determine its reliability and validity, and investigate the effect of neurocognitive load on test performance in athletes and healthy volunteers aged 18-40.\n\nThe main questions it aims to answer are:\n\nAre the developed upper extremity neurocognitive tests reliable and valid tool for assessment?\n\nDoes the addition of neurocognitive load significantly affect upper extremity physical performance scores?\n\nAre the neurocognitive performance test results related to shoulder rotator cuff muscle strength, rate of force development, and shoulder function?\n\nResearchers will compare the neurocognitive performance of athletes to healthy non-athlete individuals to see if the test battery can effectively differentiate between these two groups (discriminative validity).\n\nParticipants will:\n\nComplete demographic forms and questionnaires regarding activity level and shoulder function.\n\nUndergo shoulder range of motion and isometric strength\u002Frate of force development assessments.\n\nPerform a battery of 4 neurocognitive tests integrated with a light-based reaction system.\n\nPerform the same functional tests without neurocognitive load to serve as a baseline for comparison.\n\n(Athletes only) Attend additional sessions to evaluate the feasibility of the tests and to assess test-retest reliability with a one-week interval.",[83,26,84,85],"Athletic Performance","Cognition","Physical Functional Performance",[87,88,89,90],"shoulder","Reaction Time","Muscle Strength","Reproducibility of Results","NOT_YET_RECRUITING","2026-05-05",{"date":94,"type":32},"2026-05-12",{"date":92,"type":21},{"date":97,"type":21},"2026-07-05",{"name":99,"class":39},"Hacettepe University",{"id":101,"slug":4,"hasResults":10,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":109,"conditions":110,"keywords":129,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":139,"leadSponsor":141,"locationsCount":40},"100633082","NCT07522060","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Clinician-Developed Digital Monitoring System","HANDREHPREDICT","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Hand or upper extremity pathology requiring rehabilitation, including but not limited to: flexor or extensor tendon injuries, peripheral nerve injuries or compression syndromes (including carpal tunnel syndrome, cubital tunnel syndrome), distal radius fractures, metacarpal or phalangeal fractures, joint injuries and instabilities, arthropathy (osteoarthritis, rheumatoid arthritis), trapeziometacarpal osteoarthritis, trigger finger, Dupuytren's disease, DeQuervain tenosynovitis, lateral epicondylitis and post-surgical upper extremity conditions\n* Under clinical responsibility of the principal investigator at the Faculty of Physical Therapy and Rehabilitation, Hacettepe University\n* Expected to attend minimum 8 rehabilitation sessions\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* • Active psychiatric illness precluding participation or completion of assessment tools\n\n  * Severe cognitive impairment precluding understanding of patient-reported outcome measures\n  * Literacy difficulties preventing self-completion of questionnaires\n  * Concurrent enrollment in another interventional clinical study\n  * Refusal to provide written informed consent",{"count":108,"type":21},60,"This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later. In rehabilitation practice, clinicians make numerous decisions each session regarding exercise type, frequency, duration, and treatment approach. Most of these decisions are currently made without systematic longitudinal data. This study addresses three fundamental questions using data collected during routine clinical care: (1) Can the rate of improvement in the first weeks of treatment predict functional status months later, across both session-based and milestone-based time points? (2) Are there meaningfully different recovery profiles among hand rehabilitation patients? (3) Is there measurable variation in clinical decision-making among patients with similar profiles, and does this variation relate to outcomes? A digital patient monitoring platform developed by the principal investigator, a physiotherapist and academic researcher specializing in hand rehabilitation serves as the data collection infrastructure. The platform records standard clinical assessment measures in a structured format and has been in active clinical use at Hacettepe University prior to this study. For research purposes, the system has been expanded to include structured capture of patient-reported outcomes, patient global impression of change, treatment protocol coding, home exercise adherence, and automated calculation of early response metrics.\n\nThis is a 12-month prospective observational cohort study enrolling a minimum of 60 patients. Data are stored securely on the university's institutional network. Patients are anonymized using identification codes. The study is subject to Hacettepe University Ethics Committee approval and participant informed consent. Findings are expected to generate evidence supporting data-driven clinical decision-making in rehabilitation and to provide a feasibility foundation for a larger multi-center study.",[111,112,26,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128],"Hand","Hand Therapy","Prediction Models","Hand Injuries","Hand Injuries and Disorders","Hand Arthritis","Tendon Injuries","Wrist Fractures","Carpal Tunnel Syndrome (CTS)","Peripheral Nerve Injuries","Upper Extremity Injuries","Wrist Injuries","Finger Injuries","Trigger Finger","Trapeziometacarpal (TMC) Arthrosis","DeQuervain's Tenosynovitis","Cubital Tunnel Syndrome","Postoperative Rehabilitation",[130,131,132,133,134],"digital health monitoring","real-world evidence","clinical decision support","upper extremity rehabilitation","early response prediction","2026-04-03",{"date":137,"type":32},"2026-04-13",{"date":29,"type":21},{"date":140,"type":21},"2027-06-01",{"name":99,"class":39},{"id":143,"slug":4,"hasResults":10,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":150,"phases":151,"briefSummary":153,"conditions":154,"keywords":160,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":176},"100594073","NCT07014696","ICF-Based Effects of PNF and Kinesio Taping on Hand Function in Hemiplegic Stroke","Investigation of the Effects of PNF and Kinesiological Taping on Hand Function in Hemiplegic Stroke Patients Based on the ICF Framework","Inclusion Criteria:Inclusion criteria for the study (Junior et al., 2019; Kim \\& Kim, 2015; Saklecha et al., 2023)\n\n* Stroke diagnosed by MRI or CT, regardless of ischemic or hemorrhagic origin,\n* Hemiplegia caused by stroke alone,\n* At least 6 and at most 24 months have passed since the stroke was diagnosed\n* Being over 18 years of age,\n* Volunteering to participate in the study\n* Scoring 24 or more on the Standardized Mini Mental State Examination (if illiterate, scoring 18 or more is sufficient)\n* Cooperating with evaluation, tests and treatment\n* Understanding and speaking Turkish\n* Being at least stage 4 according to Brunnstrom staging\n\nExclusion Criteria:\n\n* Exclusion Criteria (Junior et al., 2019; Kim \\& Kim, 2015; Saklecha et al., 2023)\n* Individuals with bilateral hemiplegia\n* Individuals with unstable vital signs\n* Individuals with any open wound in the upper extremity\n* Pathological conditions affecting upper extremity sensation (undergoing surgery after fracture, etc.)\n* Individuals with a BMI value greater than 29.9 kg\u002Fm2\n* Individuals with a Standardized Mini Mental Test score below 24 points (18 points)\n* Individuals with major neurological or rheumatological disorders affecting the musculoskeletal system other than stroke (Polyneuropathy, Parkinson's, Multiple Sclerosis, Rheumatoid Arthritis, etc.)\n* Presence of upper extremity amputation\n* Being at less than stage 4 according to Brunnstrom staging",{"count":149,"type":21},54,"INTERVENTIONAL",[152],"NA","This clinical trial aims to compare the effects of kinesio taping and PNF on hemiplegic hand functions. In addition, the effects of these applications on body structure, activity, and participation will be examined. The main questions it aims to answer are:\n\nDo kinesio taping and PNF applications have different effects on hemiplegic hand function? Are kinesio taping and PNF applications effective in body structure, activity, and participation? The researchers will compare the advantages of kinesio taping and PNF applications over each other.\n\nParticipants:\n\nKinesio taping and\u002For PNF applications will be applied 3 days a week for 8 weeks.\n\nTests will be performed on the first and last day of the study to evaluate hand functions.",[155,156,157,26,158,159],"Hemiplegia","Hemiplegia Due to Stroke","Hand Functionality","Proprioceptive Neuromuscular Facilitation","Kinesio Taping",[161,162,163,62,164,165,166],"hand functionality","hemiplegia","hemiplegia due to stroke","ICF","Proprioceptive neuromuscular facilitation","kinesio taping","2026-01-13",{"date":169,"type":32},"2026-01-15",{"date":171,"type":32},"2025-06-01",{"date":173,"type":21},"2026-03-30",{"name":175,"class":39},"Istinye University",2,{"id":178,"slug":4,"hasResults":10,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":4,"eligibilityCriteria":182,"healthyVolunteers":10,"sex":183,"minAge":17,"maxAge":184,"enrollmentInfo":185,"targetDuration":4,"studyType":150,"phases":187,"briefSummary":188,"conditions":189,"keywords":193,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":40},"100598384","NCT07070791","Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer","Investigation of the Effect of Combined Upper Extremity Resistance and Aerobic Exercise Training on Arm Exercise Capacity, Peripheral Muscle Strength and Arm Functionality in Patients With Breast Cancer","Inclusion Criteria:\n\n* To be between 18-80 years old,\n* Volunteering to participate in the research,\n* At least 15 months after breast cancer surgery,\n* No problems in reading and\u002For understanding the scales and being able to co-operate with the tests.\n* Physically inactive (60 minutes of structured exercise per week \\\u003C).\n\nExclusion Criteria:\n\n* Presence of active infection,\n* Presence of bilateral breast cancer,\n* History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery,\n* Having a neurological disease or other clinical diagnosis that may affect cognitive status,\n* Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease.\n* Presence of unstable hypertension or diabetes mellitus.","FEMALE","80 Years",{"count":186,"type":21},40,[152],"According to updated data from the International Agency for Research on Cancer (IARC) for 2022, breast cancer in women is responsible for one in four cancer cases and one in six cancer deaths worldwide and is the second leading cause of global cancer incidence, accounting for 11.6% of all cancer cases, and the fourth leading cause of cancer deaths worldwide, accounting for 6.9% of all cancer deaths. During or after breast cancer treatments, there is exposure to a variety of direct (local\u002Fregional treatment, systemic treatment and supportive care) and indirect factors (modifiable and non-modifiable risk factors) that may have adverse effects on treatment-related haematological, cardiovascular, pulmonary and musculoskeletal components. Upper limb dysfunction and lymphoedema have been reported to be two of the most common side effects affecting the quality of life of breast cancer patients after breast cancer treatments. The elastic resistance band, which is widely used in strength training, has the advantage of being applied to various classes because it provides resistance angles in various postures and has a low risk of injury. However, few studies have been conducted on elastic resistance band application in patients with breast cancer. At the same time, evidence on the effectiveness of upper extremity aerobic exercise training in patients with breast cancer is limited. Therefore, this study aimed to investigate the effects of upper extremity aerobic exercise training combined with progressive resistance training and upper extremity aerobic exercise training alone on upper extremity exercise capacity, upper extremity functionality, sarcopenia, frailty, quality of life and lymphedema in patients with breast cancer.",[190,26,191,192],"Breast Cancer","Resistance Exercise","Aerobic Exercise",[194,26,195,196],"breast cancer","resistance exercise training","Aerobic exercise training","2025-12-25",{"date":199,"type":32},"2025-12-29",{"date":201,"type":32},"2025-07-08",{"date":203,"type":21},"2026-07-01",{"name":99,"class":39},{"id":206,"slug":4,"hasResults":10,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":184,"enrollmentInfo":211,"targetDuration":4,"studyType":150,"phases":212,"briefSummary":213,"conditions":214,"keywords":219,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":40},"100604586","NCT07151443","Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block","Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block in Obese Patients","Inclusion Criteria:\n\n* Patients 18-80 years of age\n* Those with ASA score II-III\n* Those with a body mass index (BMI) \\>30\n* Patients who are suitable for forearm and hand surgery under regional anesthesia in the operating room\n\nExclusion Criteria:\n\n* Patients who cannot perceive and evaluate pain\n* Patients who want to have surgery under general anesthesia\n* Patients in whom regional anesthesia is contraindicated",{"count":108,"type":21},[152],"Forearm and hand surgeries are among the most frequently performed surgical interventions both in trauma patients and electively.In these procedures, alternative anesthesia methods such as general anesthesia, regional intravenous anesthesia, regional peripheral nerve blocks and local anesthesia are available.\n\nPeripheral nerve blockade can be used for anesthesia and analgesia.This method allows patients to undergo surgery without general anesthesia and increases patient satisfaction by providing effective analgesia in the postoperative period.\n\nThe aim of this study was to compare the conventional and retroclavicular approaches to infraclavicular block in patients undergoing forearm and hand surgery.",[215,216,217,218,26],"Peripheral Nerve Block","Pain Management","Forearm Surgery","Hand Surgery",[220,221,26,222,223],"Infraclavicular Block","Obesity","Hand surgery","Forearm surgery","2025-12-08",{"date":226,"type":32},"2025-12-15",{"date":228,"type":32},"2025-09-15",{"date":230,"type":21},"2026-06-25",{"name":232,"class":233},"Ankara Etlik City Hospital","OTHER_GOV",{"id":235,"slug":4,"hasResults":10,"nctId":236,"briefTitle":237,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":10,"sex":16,"minAge":239,"maxAge":4,"enrollmentInfo":240,"targetDuration":4,"studyType":150,"phases":241,"briefSummary":242,"conditions":243,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":40},"100544013","NCT06363357","The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder","Inclusion Criteria\n\n1. Patients with a confirmed diagnosis of a neuromuscular disease (NMD) by genetic testing, muscle biopsy, or electrodiagnostic studies, presenting with prominent upper limb muscle weakness. Examples include:\n\n   1. Muscular Dystrophies: Duchenne\u002FBecker Muscular Dystrophy (DMD\u002FBMD), Limb-Girdle Muscular Dystrophy (LGMD), Facioscapulohumeral Muscular Dystrophy (FSHD), etc.\n   2. Motor Neuron Diseases: Spinal Muscular Atrophy (SMA, Types 2 and 3), Amyotrophic Lateral Sclerosis (ALS, upper limb-dominant), etc.\n   3. Peripheral Neuropathies: Charcot-Marie-Tooth (CMT) disease, etc.\n   4. Other Neuromuscular Conditions: Including but not limited to cervical spinal cord injury.\n2. Aged over 10 years.\n3. A score of 2 to 5 on the Brooke Upper Extremity Functional Rating Scale.\n4. Manual Muscle Test (MMT) grade of less than 3 for shoulder abduction.\n5. Ability to provide written informed consent from the participant and\u002For their legal representative, indicating willingness to participate in the study.\n\nExclusion Criteria\n\n1. Unwillingness or inability to provide informed consent.\n2. A score of 1 or 6 on the Brooke Upper Extremity Functional Rating Scale.\n3. Cognitive impairment severe enough to interfere with the proper use of a shoulder orthosis.\n4. Any other condition which, in the opinion of the investigator, would make study participation inappropriate or unsafe for the patient.","10 Years",{"count":79,"type":21},[152],"The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with neuromuscular disorder.\n\nThe main questions it aims to answer are:\n\n* What is the impact of the muscle-mimicking, fabric-type shoulder orthosis on upper limb functional movements in patients with neuromuscular disorder?\n* Are there observable differences in upper limb function when the shoulder orthosis is worn versus when it is not?\n\nParticipants will:\n\n* Receive education on how to wear and use the shoulder orthosis.\n* Undergo evaluations, including assessment of upper limb performance, shoulder muscle strength testing, active range of motion measurements, assessment of functional workspace, goal attainment scale evaluation, surface electromyography, physiological measurements such as blood pressure and heart rate, fatigue assessment, and assessment for any musculoskeletal or skin-related issues.\n\nResearchers will compare neuromuscular disorder patients before and while wearing and operating the shoulder orthosis to see if there are any significant effects on variables such as upper limb function, range of motion, functional workspace, goal attainment scale, and surface electromyography.",[244,245,26,246,247,248,249,250,251],"Muscular Dystrophy, Duchenne","Orthotic Devices","Neuromuscular Diseases (NMD)","Fascioscapulohumeral Muscular Dystrophy","Spinal Muscular Atrophy (SMA)","ALS (Amyotrophic Lateral Sclerosis)","LGMD","SCI - Spinal Cord Injury","2025-11-25",{"date":254,"type":32},"2025-12-03",{"date":256,"type":32},"2024-04-20",{"date":258,"type":21},"2025-12-31",{"name":260,"class":39},"Seoul National University Hospital",{"id":262,"slug":4,"hasResults":10,"nctId":263,"briefTitle":264,"officialTitle":265,"acronym":4,"eligibilityCriteria":266,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":267,"enrollmentInfo":268,"targetDuration":4,"studyType":150,"phases":270,"briefSummary":271,"conditions":272,"keywords":277,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":40},"100609160","NCT07210944","Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study","Research Protocol for a Randomized Controlled Trial on Brain Network Study of Upper Limb Motor Dysfunction in Stroke Patients Treated With Scalp Acupuncture Combined With rTMS","Inclusion Criteria:\n\n* Meet the diagnostic criteria for stroke (symptoms and signs, imaging indicators, etc.), and are independently diagnosed by two deputy chief physicians\n* Age 18-70 years old, first episode, duration 1-6 months\n* The diagnostic criteria for upper limb dysfunction align with the Brunnstrom staging system: patients in Brunnstrom stages II to IV. Stage II: patients exhibit associative responses and can perform coordinated movements, with minimal voluntary movements; Stage III: patients show voluntary coordinated movements, such as grasping with the hand but not extending; Stage IV: patients can perform isolated movements, such as pinching with the hand and limited extension\n* No severe visual or hearing impairment, able to cooperate with relevant assessments and tests\n* The score of the Mini-Mental State Examination is ≥20 points\n* Vital signs are stable, with no signs of progressive neurological symptoms\n* The patient or legal guardian agrees and signs the informed consent form\n\nExclusion Criteria:\n\n* Severe visual impairment, hemispatial neglect, body image disorder\n* Individuals who cannot undergo rTMS treatment due to reasons such as metal implants, cardiac pacemakers, or skull defects\n* Previous history of brain tumor, brain trauma, epilepsy, and risk of epileptic seizures\n* Any other factors that affect assessment and treatment\n* Dysfunction of limb movement caused by other reasons (such as trauma, etc.)","70 Years",{"count":269,"type":21},44,[152],"This study aims to compare the improvement effects of the rTMS (repetitive transcranial magnetic stimulation) combined with conventional rehabilitation therapy group with the rTMS combined with scalp acupuncture and conventional rehabilitation therapy group. Through statistical analysis of the results obtained from functional near-infrared spectroscopy technology during task states, the investigators elucidate the neuroregulatory mechanism of scalp acupuncture combined with rTMS in improving upper limb motor function in stroke patients under MEP localization, and provide evidence for a more optimal rehabilitation program for post-stroke upper limb motor dysfunction.",[26,273,274,275,276],"Acupuncture Therapy","Stroke","Transcranial Magnetic Stimulation Repetitive","Motor Disorders",[278,279,280,281,276],"Conventional rehabilitation therapy","Scalp Acupuncture","Upper Limb","Repetitive Transcranial Magnetic Stimulation","2025-11-18",{"date":284,"type":32},"2025-11-19",{"date":286,"type":21},"2025-12-05",{"date":288,"type":21},"2027-05-30",{"name":290,"class":39},"Debiao Kong",{"id":292,"slug":4,"hasResults":10,"nctId":293,"briefTitle":294,"officialTitle":295,"acronym":4,"eligibilityCriteria":296,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":297,"enrollmentInfo":298,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":300,"conditions":301,"keywords":304,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":307,"lastUpdatePostDateStruct":308,"startDateStruct":310,"completionDateStruct":312,"leadSponsor":314,"locationsCount":40},"100589015","NCT06948916","Validity and Reliability of 6-minute Pegboard and Ring Test in Patients With Interstitial Lung Disease","Investigation of the Validity and Reliability of 6-minute Pegboard and Ring Test in Patients With Interstitial Lung Disease","Inclusion Criteria:\n\n* Patients diagnosed with ILD according to ATS\u002FERS criteria,\n* Ages between 18 and 75,\n* Pulmonary infection during the previous month,\n* Participants who voluntarily participated in the study were included.\n\nExclusion Criteria:\n\n* Patients were excluded if they had:\n* Acute pulmonary exacerbation or respiratory infection in the last four weeks\n* Obstructive lung disease\n* Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions\n* Recent participation in a planned exercise program (within three months)\n* Cognitive impairment affecting exercise test understanding\n* Contraindications to exercise testing per the American Sports Medicine Association\n* Cancer, renal, or hepatic disease\n* Aortic stenosis, complex arrhythmia, or aortic aneurysm\n* Serious cardiovascular diseases like uncontrolled hypertension, diabetes, heart failure, or arrhythmia","75 Years",{"count":299,"type":21},34,"Interstitial lung diseases (ILD) are a heterogeneous group of chronic respiratory diseases that cause significant mortality and morbidity worldwide, characterized by diffuse inflammation in the lung parenchyma and vascular structures, can progress to fibrosis, have known or unknown etiology, and can develop secondary to systemic autoimmune connective tissue diseases other than diseases where the primary pathology is in the lung. The 6-minute peg-board and ring test, which was first developed to determine the upper extremity exercise capacity of chronic obstructive pulmonary disease patients, is an exercise test used to evaluate upper extremity functional exercise capacity in different lung diseases. It has been determined that there is no study on the validity and reliability of this test in individuals with ILD.",[302,303,26],"Interstitial Lung Diseases (ILD)","Exercise Capacity",[305,303,306],"Interstitial lung diseases","Upper extremity","2025-04-22",{"date":309,"type":32},"2025-04-29",{"date":311,"type":32},"2024-12-12",{"date":313,"type":21},"2025-08-12",{"name":315,"class":39},"Gazi University",""]