[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"uterus-abnormal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:uterus-abnormal":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100539771",false,"NCT06308172","Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial","Inclusion Criteria:\n\n* nulliparous\n* singleton\n* age 18-45\n* spontaneous pregnancy or autologous assisted fertilization\n* gestational age 38-40 weeks\n* elective C-section\n* informed consent\n\nExclusion Criteria:\n\n* coagulopathy\n* autoimmune diseases\n* gestational diabetes\n* anticoagulant therapy\n* immunosuppressive therapy\n* endometriosis\n* uterine fibromatosis\n* spontaneous labour\n* connective tissue diseases","FEMALE","18 Years",{"count":17,"type":18},150,"ESTIMATED","INTERVENTIONAL",[21],"NA","The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups",[24,25,26,27,28],"Cesarean Section; Dehiscence","Uterine Bleeding","Uterus; Scar","Uterus Abnormal","Cesarean Section Complications","RECRUITING","2024-03-06",{"date":32,"type":33},"2024-03-13","ACTUAL",{"date":35,"type":33},"2021-12-01",{"date":37,"type":18},"2026-12-01",{"name":39,"class":40},"Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico","OTHER",""]