[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vaginal-flora-imbalance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vaginal-flora-imbalance":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100488483",false,"NCT05640700","Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia","Assessing Personalized Vaginal Microbiome Contributions to HPV-driven Pre-malignant and Malignant Cervical Cancer","Inclusion Criteria:\n\n* Age 25-70\n* Attended the clinic for a Pap smear or colposcopy\n\nExclusion Criteria:\n\n* Patient does not approve sample collection\n* Usage of antibiotics in the month prior to clinic visit\n* Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)\n* Menstruation\n* Pregnancy",true,"FEMALE","25 Years","70 Years",{"count":20,"type":21},90,"ESTIMATED","OBSERVATIONAL","In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.",[25,26,27,28],"Human Papilloma Virus","Vaginal Flora Imbalance","Cancer Cervix Uterus","Cervical Dysplasia","RECRUITING","2025-03-15",{"date":32,"type":33},"2025-03-19","ACTUAL",{"date":35,"type":33},"2022-11-09",{"date":37,"type":21},"2025-12-30",{"name":39,"class":40},"Hadassah Medical Organization","OTHER",""]