[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"virtual-reality\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:virtual-reality":626},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,110,0,25,[9,49,78,103,129,156,180,203,226,249,271,294,313,336,358,382,408,432,459,482,502,524,545,574,595],{"id":10,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":48},"100625767",false,"NCT07426913","Cardiovascular Health Education Via Virtual Reality for Breast Cancer Survivors Receiving Anthracyclines or Trastuzumab","Cardiovascular Health Education Via Virtual Reality for Breast Cancer Survivors Receiving Anthracyclines or Trastuzumab - Phase 2","Inclusion Criteria:\n\n* 18 years of age or older\n* Able to speak and read in English\n* Actively receiving Trastuzumab or an anthracycline-based treatment\n* Currently receiving immunotherapy. This includes pembrolizumab and atezolizumab.\n* Diagnosed with stages 0-III Breast Cancer\n\nExclusion Criteria:\n\n\\- History of prior Breast Cancer diagnosis (i.e., not their first breast cancer diagnosis)","FEMALE","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","The main goal of this study is to test a virtual reality (VR) program, Survivors' Virtual Reality Survivorship Experience (SurviVRSE), designed to help Breast Cancer survivors (n=30) learn about heart health. The aims are to test the usability, feasibility, and acceptability o the intervention. Additionally, follow-up assessments will examine changes in women's cancer therapy related cardiac dysfunction knowledge and heart healthy behaviors (e.g., physical activity).",[26,27,28,29],"Breast Cancer","Anthracycline Related Cardiotoxicity in Breast Cancer","Virtual Reality","Trastuzumab",[31,32,33,34,35,36],"virtual reality","breast cancer","antracyclines","trastuzumab","VCU","Virginia Commonwealth University","RECRUITING","2026-07-01",{"date":40,"type":41},"2026-07-02","ACTUAL",{"date":43,"type":41},"2026-05-20",{"date":45,"type":20},"2027-02-28",{"name":36,"class":47},"OTHER",3,{"id":50,"slug":4,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":66,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100645034","NCT07677436","Effect of Virtual Reality-Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy","Effect of Virtual Reality Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial","VRGI-Chemo Tri","Inclusion Criteria:\n\n* Female patients aged 18 years or older.\n* Histologically confirmed breast cancer.\n* Stage I, II, or III breast cancer.\n* Underwent surgery as the initial treatment and are scheduled to receive the first cycle of adjuvant chemotherapy, with or without biologic therapy (e.g., AC or TC regimens).\n* Able to read, write, and communicate.\n* Able and willing to use a virtual reality headset.\n* Able to provide written informed consent.\n\nExclusion Criteria:\n\n* Visual or hearing impairment that prevents the use of virtual reality.\n* Serious neurological or psychiatric disorders.\n* Current participation in other non-pharmacological interventions (e.g., meditation or relaxation therapy) that could influence the study outcomes.\n* Previous experience with virtual reality-guided imagery.\n* Use of analgesics, anxiolytics, or other medications during the intervention that may affect the study outcomes.",{"count":57,"type":20},108,[23],"This randomized controlled trial aims to evaluate the effectiveness of virtual reality-guided imagery in reducing pain, anxiety, and fatigue among female breast cancer patients undergoing adjuvant chemotherapy. Participants will be randomly assigned to either an intervention group receiving virtual reality-guided imagery in addition to routine care, or a control group receiving routine care",[28,61,26,62,63,64,65],"Guided Imagery","Chemotherapy","Pain","Anxiety","Fatigue",[67],"Virtual Reality, Guided Imagery , Breast Cancer, Chemotherapy , Pain, Anxiety , Fatigue","NOT_YET_RECRUITING","2026-06-27",{"date":71,"type":41},"2026-06-30",{"date":38,"type":20},{"date":74,"type":20},"2027-03",{"name":76,"class":47},"Thoalfokar Mohammed Al-Obaidi",1,{"id":79,"slug":4,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":21,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100548688","NCT06424249","Dynamic Balance in Unilateral Transtibial Amputees Following Virtual Reality Versus Conventional Rehabilitation","EQUIL-ARC","Inclusion Criteria:\n\n* Unilateral transtibial amputees in hospitalized in the rehabilitation of the musculoskeletal system service\n* All etiologies: vascular, traumatic and septic.\n* Adapted vascular equipment validated by physician.\n* Able to walk for 5 minutes on a treadmill without technical assistance.\n* The patient must have given their free and informed consent and signed the consent form\n* The patient must be a member or beneficiary of a health insurance plan\n\nExclusion Criteria:\n\n* The subject is participating in an interventional study or one involving a drug or medical device, or is in a period of exclusion determined by a previous study\n* Patient already included in the present study.\n* The subject refuses to or is unable to sign the consent\n* It is impossible to give the subject informed information\n* The patient is under safeguard of justice or state guardianship\n* Patients with uncorrected or untreated visual disorders.\n* Patients with major cognitive disorders (MOCA\\>23).\n* Patients with vestibular disorders.\n* Patient with uncontrolled epilepsy.\n* Patient with an unhealed amputation stump.\n* Patients weighing \\> 135kg or \\\u003C 20kg.\n* Patients with a functional ambulation category of 1 (i.e. patients requiring the firm, continuous assistance of another person to carry their weight and maintain their balance) or less.\n* Patients with medication affecting exercise tolerance,\n* Patients with sensory impairments\n* Patients with significantly reduced bone density\n* Patients for whom it is impossible to correctly adjust the harness to the corresponding body part due to:\n\n  * Body shape\n  * Colostomy bags\n  * Skin lesions that cannot be adequately protected.\n  * Any other reason that prevents proper, pain-free adjustment of the sling.\n* Pregnant, parturient or breast-feeding patients.\n* Appearance of a stump wound during the study requiring discharge.\n* Patient with more than 50% absenteeism from rehabilitation sessions.\n* Patient requiring a new prosthesis insert.\n* Patient with a serious adverse event affecting dynamic balance rehabilitation.","ALL","80 Years",{"count":87,"type":20},20,[23],"Amputation causes somatic and psychological damage. Prognostic factors for postoperative gait recovery include the need for proprioceptive re-education for dynamic balance. Improved gait patterns and use of the prosthesis contribute to an overall improvement in the amputee's autonomy. Virtual reality coupled with movement analysis allows personalization of treatment with objective assessment of progress.\n\nThe study authors hypothesize that a virtual reality protocol for the dynamic balance of a unilateral transtibial amputee in initial rehabilitation will improve the dynamic balance assessment criteria compared with a conventional rehabilitation protocol.",[91,28,92],"Amputees \u002F Rehabilitation","Postural Balance","2026-06-23",{"date":95,"type":41},"2026-06-25",{"date":97,"type":41},"2024-10-14",{"date":99,"type":20},"2026-12",{"name":101,"class":47},"Centre Hospitalier Universitaire de Nīmes",2,{"id":104,"slug":4,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":108,"sex":84,"minAge":17,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":112,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":77},"100594040","NCT07014267","Virtual Reality for Mindfulness and Anxiety Reduction in Fertility Procedures","Inclusion Criteria:\n\n* Patients aged 18-50.\n* Scheduled for fertility-related surgical procedures.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* History of motion sickness or VR-related discomfort.\n* Cognitive or psychological conditions affecting participation.\n* Procedures requiring emergency intervention.",true,"50 Years",{"count":111,"type":20},500,[23],"This study aims to evaluate the effectiveness of a Virtual Reality (VR)-based mindfulness and meditation intervention in reducing anxiety among patients undergoing fertility-related surgical procedures. Anxiety is a common challenge in fertility treatments, often leading to emotional distress and increased pain perception. By incorporating a non-invasive VR intervention, the investigators seek to improve patient experience, minimize preoperative anxiety, and potentially reduce postoperative discomfort and recovery times. This randomized controlled trial (RCT) will compare standard care with a VR intervention in a clinical setting, measuring key outcomes such as anxiety levels, pain perception, recovery duration, and overall patient satisfaction. The findings may contribute to more patient centered fertility care, offering an innovative, scalable, and cost-effective approach to anxiety management in reproductive medicine.",[28,115],"Patient Experience",[117,118,119,120,31],"anxiety","stress","pain perception","recovery duration","2026-06-22",{"date":95,"type":41},{"date":124,"type":41},"2025-07-10",{"date":126,"type":20},"2026-12-31",{"name":128,"class":47},"ART Fertility Clinics LLC",{"id":130,"slug":4,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":84,"minAge":135,"maxAge":136,"enrollmentInfo":137,"targetDuration":139,"studyType":140,"phases":4,"briefSummary":141,"conditions":142,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":77},"100641165","NCT07656389","An AI-Based Prediction of Cognitive Capacity in Older Adults and Individuals With Mild Cognitive Impairment During Virtual Reality Driving Tasks","From Eye Movements to Visuomotor Coupling: An AI-Based Prediction of Cognitive Capacity in Older Adults and Individuals With Mild Cognitive Impairment During Virtual Reality Driving Tasks","Inclusion Criteria:\n\n* (1) a score of 23 or higher on the Montreal Cognitive Assessment; (2) a Clinical Dementia Rating score of 0 for cognitively healthy participants or 0.5 for participants with mild cognitive impairment (MCI); (3) healthy young adults aged between 30 and 39 years, and cognitively healthy older adults and participants with MCI aged between 65 and 85 years; (4) right-hand dominance; and (5) adequate visual function to complete VR and eye-tracking tasks, defined as corrected binocular visual acuity of at least 0.5 without severe visual field deficits.\n\nExclusion Criteria:\n\n* (1) the presence or history of major psychiatric disorders or central nervous system diseases; (2) significant ocular diseases, such as untreated cataracts, active retinal diseases, moderate-to-severe or poorly controlled glaucoma, or marked visual field deficits beyond a specified level; (3) epilepsy; and (4) severe dizziness or VR-induced motion sickness.","30 Years","85 Years",{"count":138,"type":20},192,"12 Months","OBSERVATIONAL","Driving ability in older adults is essential for independent mobility and social participation, yet declines under high cognitive load or distraction often lead to visual attention failures such as \"look-but-fail-to-see,\" increasing crash risk. Older adults and individuals with mild cognitive impairment (MCI) show impairments in visual attention, executive control, and visuomotor integration, which are not adequately captured by conventional assessments. Virtual reality (VR) integrated with eye-tracking and upper-limb motion analysis enables ecologically valid simulation of driving scenarios and precise quantification of visuomotor behavior. However, current studies are limited by single-scenario designs, unimodal AI models, and insufficient integration of action-related data.\n\nThis study proposes a multi-phase framework: Year 1 develops an eye-movement-based AI model for MCI identification; Year 2 integrates multimodal data in VR driving tasks; and Year 3 establishes an explainable AI system with longitudinal validation. The study aims to advance cognitive assessment and develop a digital tool for early MCI detection and driving risk prediction.",[143,28,144,145,146],"Mild Cognitive Impairment (MCI)","Eye Movement Disorder","Multimodal Monitoring","Older Adults","2026-06-14",{"date":149,"type":41},"2026-06-18",{"date":151,"type":20},"2026-06-20",{"date":153,"type":20},"2029-12-31",{"name":155,"class":47},"National Cheng-Kung University Hospital",{"id":157,"slug":4,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":108,"sex":84,"minAge":162,"maxAge":85,"enrollmentInfo":163,"targetDuration":4,"studyType":21,"phases":165,"briefSummary":166,"conditions":167,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":77},"100633363","NCT07525713","Virtual Reality Mirror Therapy With Focused Object-Directed Attention System","Virtual Reality Mirror Therapy With Focused Object-Directed Attention for Neuro-Rehabilitation","Inclusion Criteria:\n\n* Clinical diagnosis of stroke with unilateral side involved;\n* A score of Mini-mental state examination greater than 24 for proving higher mental function;\n* Time of onset \\> 6 months before treatment begins;\n* Premorbid right-handedness.\n\nExclusion Criteria:\n\n* Severe vision impairment;\n* Major cognitive-perceptual deficit;\n* Other brain disease.","20 Years",{"count":164,"type":20},54,[23],"In this study, the investigators hypothesized that Virtual Reality Mirror Therapy with Focused Object-Directed Attention (VRMTFOA) would yield superior therapeutic effects compared to conventional Virtual Reality Mirror Therapy (VRMT) in individuals with unilateral stroke.\n\nThe aim of this study is to compare the immediate effects of a single session of VRMT, VRMTFOA, and VRMTFOA with auditory feedback on upper extremity function and brain activity in stroke patients.",[168,169,28,170,171,172],"Stroke","Rehabilitation","Mirror Movement Therapy","Attention","Task Performance",{"date":174,"type":41},"2026-06-16",{"date":176,"type":41},"2026-04-20",{"date":178,"type":20},"2027-12-31",{"name":155,"class":47},{"id":181,"slug":4,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":183,"acronym":184,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":186,"targetDuration":4,"studyType":21,"phases":188,"briefSummary":189,"conditions":190,"keywords":192,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":194,"lastUpdatePostDateStruct":195,"startDateStruct":197,"completionDateStruct":199,"leadSponsor":201,"locationsCount":77},"100481296","NCT05547152","Evaluation of the Effectiveness of Virtual Reality Self-rehabilitation in the Treatment of Facial Paralysis and Synkinesis","RéMiFaSy","Inclusion Criteria:\n\n* Patient with recent onset peripheral facial palsy (≤ 12 months).\n* Patient with peripheral facial palsy of grade ≥ III on the House \\& Brackmann score\n* Patient of legal age (≥ 18 years)\n* Patient with appropriate information and informed consent\n\nExclusion Criteria:\n\n* Patient with central facial palsy\n* Patient with peripheral facial palsy of \\> 12 months onset\n* Patient with peripheral facial palsy of grade \\\u003C III House \\& Brackmann score\n* Patient who has previously undergone palliative surgery\n* Patient undergoing a botulinum toxin injection protocol\n* Patients benefiting from enhanced protection, i.e. minors, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social institution, adults under legal protection, pregnant or breast-feeding women and patients in emergency situations\n* Patients who have not provided informed consent\n* Patients with cognitive disorders that do not allow them to follow the proposed self-education protocol\n* Blind or visually impaired patients (visual acuity of the better eye after correction ≤ 4\u002F10)",{"count":187,"type":20},100,[23],"Peripheral facial palsy affects 15 to 40 people per 100,000 inhabitants and induces important functional and social repercussions. Synkinesis is a frequent after-effect of facial palsy recovery, consisting of involuntary facial spasms that disturb the gestural harmony and can go as far as a painful hypertonic spasm. More than 55% of patients recovering from facial palsy will develop transient or permanent synkinesis. These facial hypertonias have two main causes: imperfect axonal regeneration, which is all the more important as the damage is proximal, and hyperexcitability of the facial nerve nucleus due to a lack of central control. Management is therefore essential for the functional restoration of the face, especially since synkinesis do not evolve spontaneously. The main treatments are currently botulinum toxin injection, acting on the motor plate, and functional rehabilitation, consisting on local muscle relaxation and central motor control work. In recent years, therapies based on biofeedback and acting on central motor control have shown interesting results, and technological advances in virtual reality have made it possible to deepen this treatment in patients suffering from stroke, limb trauma or Parkinson's disease. In this project, the investigators evaluate the contribution of virtual reality to the management of facial palsy, and hypothesize that self-rehabilitation using this technology will improve motor control of the skin muscles and reduce complications related to their hypertonia such as synkinesis.",[191,169,28],"Peripheral Facial Palsy",[191,193,31],"rehabilitation","2026-06-12",{"date":196,"type":41},"2026-06-15",{"date":198,"type":41},"2022-08-02",{"date":200,"type":20},"2029-08",{"name":202,"class":47},"Centre Hospitalier Universitaire, Amiens",{"id":204,"slug":4,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":11,"sex":84,"minAge":210,"maxAge":4,"enrollmentInfo":211,"targetDuration":4,"studyType":21,"phases":213,"briefSummary":214,"conditions":215,"keywords":217,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":77},"100602092","NCT07119008","Use of Virtual Reality as a Tool for Cognitive Remediation in Elderly Depressed Patients","Use of Virtual Reality as a Cognitive Remediation Tool in the Depressed Elderly Subject","REVIVED","Inclusion Criteria:\n\n* Patients aged 70 or over;\n* Patient with a characterized depressive episode as assessed by the GDS (Score \\> 13 at inclusion);\n* Patient with a minimum MMS score of 23\u002F30 at inclusion;\n* Patient affiliated to or benefiting from a social security scheme;\n* Patient having received information on the protocol and having given free, informed and written consent.\n\nExclusion Criteria:\n\n* Patients suffering from epilepsy;\n* Patients suffering from inner ear disorders;\n* Patients with balance disorders or postural instability;\n* Patients with swallowing disorders requiring mixed feeding;\n* Patients suffering from migraines;\n* Patients with major sensory deficits (visual or auditory);\n* Patients suffering from eye pathologies or abnormalities, and whose condition strictly contraindicates virtual reality;\n* Patients suffering from oculo-motor disorders;\n* Patients with sensory-motor deficits affecting the upper limb(s) that prevent them from performing the tasks required during VR sessions;\n* Patients suffering from primary neuropathic disorders or secondary to metabolic pathologies;\n* Patients suffering from acute psychiatric decompensation that makes it impossible for them to cooperate with the sessions (opposition, agitation, acute delusions, hallucinations, panic attacks);\n* Patients with uncontrolled cardiac pathology (angina, heart failure, rhythm disorders, conduction disorders);\n* Patients with uncontrolled hypertension (SBP \\> 140 mmHg and DBP \\> 90 mmHg in patients with traited hypertension);\n* Patients with implanted medical devices (pacemakers, defibrillators, etc.);\n* Patients under legal protection (guardianship) or deprived of liberty.\n* Patients who do not speak or read French fluently, unable to understand the principle of the study questionnaires and unable to cooperate with the tests.","70 Years",{"count":212,"type":20},40,[23],"Depression, the most common mental disorder affecting the elderly, represents a major public health issue. This pathology leads to a loss of activity and autonomy in the elderly. It impairs executive skills, enabling a person to take initiatives, perform goal-oriented actions and adapt to new situations. Impaired executive functions greatly increase the risk of loss of autonomy and institutionalization, as well as the burden on caregivers. Antidepressant treatments have little or no effect on cognitive disorders. It therefore appears necessary to offer these patients specific treatment of these cognitive symptoms. The investigators are interested in cognitive remediation based on virtual reality (VR) for its ecological and modular characteristics, the innovative aspect of this technique, the appeal of virtual experiences, and their easy access to the general public. The main objective of this study is to demonstrate the acceptability of the VR technique in a population of subjects aged 70 and over, suffering from cognitive disorders and associated depression.\n\nIn this study the investigators support the use of VR as a tool for cognitive remediation and ecological staging of their interactions with caregivers in the face of executive disorders found in patients suffering from depression. By improving their cognitive skills, VR brings greater autonomy and improved quality of life for patients and their caregivers. The investigators therefore plan to use a virtual environment to create scenarios that reproduce real-life situations, which appear to be more relevant than conventional cognitive remediation exercises.\n\nThe investigators chose acceptability as the main criterion for this technique, as the elderly population is identified as a sensitive population in the opinion issued by ANSES in June 2021. What's more, this population is often excluded from the new digital technologies; it therefore seems interesting to look at the acceptability of virtual reality by this elderly population.",[28,216],"Depression",[31],"2026-06-10",{"date":194,"type":41},{"date":221,"type":20},"2026-09-01",{"date":223,"type":20},"2028-11-01",{"name":225,"class":47},"University Hospital, Brest",{"id":227,"slug":4,"hasResults":11,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":231,"eligibilityCriteria":232,"healthyVolunteers":108,"sex":84,"minAge":233,"maxAge":4,"enrollmentInfo":234,"targetDuration":4,"studyType":21,"phases":235,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":48},"100642586","NCT07644416","Using Virtual Reality Travel to Reduce Loneliness in Older Adults","Virtual Reality Travel (VRT) as a Loneliness Intervention for Older Adults: A Pilot Randomized Controlled Trial","VRT","Inclusion Criteria:\n\n* Adults aged 65 years or older\n* Express willingness to engage with VR technology\n\nExclusion Criteria:\n\n\\- No self-reported physical, sensory, neurological, or cognitive conditions that would make VR use unsafe or impractical (e.g., uncontrolled seizures, severe vertigo, or significant uncorrected vision\u002Fhearing impairments).","65 Years",{"count":212,"type":20},[23],"This study aims to investigate whether and how virtual reality travel (VRT) can reduce loneliness among older adults. It will utilize a mixed-methods research design that combines an randomly assigned experiment with follow-up semi-structured interviews.\n\nThis is a pilot study and it is essential to establish the feasibility and acceptability of the protocol, assess the tolerability of VR technology in this population prior to conducting a full-scale RCT, and generate preliminary effect size estimates to inform future sample size calculations.",[238,239,28,240],"Loneliness","Older Adults (65 Years and Older)","Leisure Activities","2026-06-08",{"date":194,"type":41},{"date":244,"type":20},"2026-06-01",{"date":246,"type":20},"2027-05-30",{"name":248,"class":47},"Indiana University",{"id":250,"slug":4,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":21,"phases":257,"briefSummary":258,"conditions":259,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":269,"locationsCount":77},"100584757","NCT06893510","Virtual Reality-Based and Face-to-Face Relaxation Programs in Pregnant Women With Preeclampsia","The Effect of Virtual Reality-Based and Face-to-Face Relaxation Programs on Maternal and Fetal Outcomes in Pregnant Women With Preeclampsia","Inclusion Criteria:\n\n* Hospitalized with a diagnosis of preeclampsia.\n* Gestational age ≥26 weeks.\n* 18 years or older.\n* Singleton and viable pregnancy.\n* Willing to participate in the study voluntarily.\n\nExclusion Criteria:\n\n* Multiple pregnancy.\n* Pregnancy achieved through assisted reproductive technologies.\n* Hearing or vision impairment in the pregnant individual.\n* Fetal distress requiring emergency intervention.\n* HELLP Syndrome or Eclampsia.\n* History of vertigo.\n\nWithdrawal Criteria:\n\n* Cases where live birth does not occur.\n* Participants who voluntarily withdraw from the study.\n* Participants whose general health condition deteriorates during the intervention.\n* Participants experiencing side effects from virtual reality headset use (e.g., dizziness, nausea, headache).\n* Participants who do not practice progressive muscle relaxation at least once a week after the intervention.",{"count":256,"type":20},96,[23],"Preeclampsia, affecting 2-8% of pregnancies globally, is a leading hypertensive disorder in pregnancy. It is clinically characterized by elevated blood pressure (≥140\u002F90 mmHg) after the 20th gestational week, often accompanied by proteinuria and systemic complications such as thrombocytopenia, liver dysfunction, and cerebral symptoms. This condition poses significant risks for both maternal and fetal health, increasing the likelihood of organ damage, preterm birth, and long-term cardiovascular and neurodevelopmental complications. Non-pharmacological interventions, including relaxation techniques, have been explored for symptom management. Progressive muscle relaxation (PMR) has shown efficacy in reducing stress, anxiety, and blood pressure. Recently, virtual reality (VR)-based relaxation techniques have gained attention for enhancing stress relief and improving health outcomes. This study aims to compare the effects of VR-based PMR with in-person PMR on maternal and fetal outcomes in preeclamptic pregnancies.",[260,261,262,28,263],"Pre-Eclampsia","Maternal Health","Relaxation","Fetal Monitoring","2026-06-07",{"date":218,"type":41},{"date":267,"type":41},"2025-09-08",{"date":221,"type":20},{"name":270,"class":47},"Istanbul University - Cerrahpasa",{"id":272,"slug":4,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":274,"acronym":275,"eligibilityCriteria":276,"healthyVolunteers":11,"sex":84,"minAge":277,"maxAge":17,"enrollmentInfo":278,"targetDuration":4,"studyType":21,"phases":280,"briefSummary":281,"conditions":282,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":77},"100434220","NCT04934293","Virtual Reality for Children in Radiotherapy (REVER)","REVER","Inclusion Criteria:\n\n* Patient treated at the Antoine LACASSAGNE Center for treatment by proton therapy\n* Age ≥ 7 years old and ≤ 18 years old\n* Patient, and parents for minor children, having read the information notice and signed the informed consent,\n* Patient with social security coverage.\n\nExclusion Criteria:\n\n* Age \\\u003C 7 years old and \\> 18 years old,\n* Patient under general anesthesia,\n* Patient suffering from wounds or infections in the head, deemed incompatible with the use of the helmet by the investigator,\n* Patient suffering from respiratory problems,\n* Patient suffering from a high level of claustrophobia,\n* Patient followed for a psychiatric pathology,\n* Patient suffering from unbalanced epilepsy,\n* Patient suffering from visual (binocular vision) and \u002F or hearing disorders preventing the use of virtual reality,\n* Patient whose head circumference is insufficient for the use of the helmet, deemed incompatible with the use of the helmet by the investigator,\n* Patient treated by radio chemotherapy.","7 Years",{"count":279,"type":20},47,[23],"For a young patient, the conditions of proton therapy treatment can be stressful. Adjusting the environment can be a source of avoiding this physical and psychological discomfort impacting the quality of treatment.\n\nA fixed, long, uncomfortable position is the main cause of stress, already present due to the cancerous therapeutic course. It extends the positioning time. For the patient and the optimization of his treatment, solutions must be sought.\n\nRelaxation in virtual reality is efficient, simple and non-medicinal and could reduce stress in children and allow irradiation in very good conditions.\n\nWe will assess the effectiveness of the virtual reality session using objective (placement time, helmet tolerance) and subjective (perceived anxiety via a dedicated questionnaire) criteria. This is the first pediatric virtual reality study, supported by the French Group of Pediatric Radiotherapists, to reduce anxiety in radiotherapy.\n\nMultiple benefits from this pilot study are expected, such as improved reception conditions, treatment parameters and better acceptance of proton therapy sessions.",[28,283,284],"Proton Therapy","Pediatric Cancer","2026-05-27",{"date":287,"type":41},"2026-05-29",{"date":289,"type":41},"2021-08-02",{"date":291,"type":20},"2027-02",{"name":293,"class":47},"Centre Antoine Lacassagne",{"id":295,"slug":4,"hasResults":11,"nctId":296,"briefTitle":297,"officialTitle":297,"acronym":4,"eligibilityCriteria":298,"healthyVolunteers":108,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":21,"phases":300,"briefSummary":301,"conditions":302,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":77},"100638584","NCT07620639","Consciousness Studies and Cardiovascular Health","Inclusion Criteria:\n\n* Age 18 and older\n* Able to provide informed consent (English only for pilot)\n* Chronic Selective Serotonin Reuptake Inhibitors\u002F Serotonin-norepinephrine reuptake inhibitors (SSRI\u002FSNRI) or Attention Deficit\u002F Hyperactivity Disorder (ADHD) meds allowed (recorded)\n* Normal vision and hearing\n* Stable vitals (HR 55-100 bpm, Systolic Blood Pressure (SBP) 90-160mmHg (millimeters of mercury, afebrile)\n* Willing to abstain 6 hours pre-session from caffeine, nicotine, heavy exercise\n* Willing to tolerate electroencephalogram (EEG) headband, Galvanic Skin Response (GSR) electrodes are small sensors placed on the skin (usually fingers or palm) and virtual reality (VR) headset\n\nExclusion Criteria:\n\n* History of seizure disorder or photosensitive epilepsy\n* Migraine with visual aura\n* Retinal disease sensitive to flicker\n* Unstable cardiac disease\n* Dysautonomia\n* Recent sedative use (benzodiazepines, opioids)\n* Beta blocker dose changes within last 7 days\n* Alcohol or recreational drugs within 12 hours\n* Active panic disorder\n* Severe motion sickness\n* Scalp conditions preventing EEG contact\n* Severe visual or hearing impairment Cognitive impairment\n* Non-English speakers (pilot in English only)",{"count":212,"type":20},[23],"The objective of the study is to evaluate whether a virtual reality (VR) based intervention combining binaural beats, photic stimulation, and real-time biofeedback reduces stress and improves physiological markers compared to non-VR interventions and usual care in patients that go to cardiology clinic.",[303,262,28],"Blood Pressure","2026-05-26",{"date":306,"type":41},"2026-06-02",{"date":308,"type":20},"2026-10",{"date":310,"type":20},"2028-10",{"name":312,"class":47},"University of Miami",{"id":314,"slug":4,"hasResults":11,"nctId":315,"briefTitle":316,"officialTitle":317,"acronym":318,"eligibilityCriteria":319,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":320,"targetDuration":4,"studyType":21,"phases":321,"briefSummary":322,"conditions":323,"keywords":325,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":77},"100617896","NCT07324577","Effectiveness of Virtual Reality (VR) in the Management of Anxiety for Patients Undergoing Radiotherapy","Effectiveness of Virtual Reality in the Management of Anxiety for Patients Undergoing Radiotherapy","RELAX","Patients:\n\nInclusion Criteria:\n\n* Participants planned for radiation therapy for 15 or more treatments with non-neutron generating energies (10 MV or less) per study PI for prostate, breast, lung, or head and neck cancer. Neutrons have the potential to damage the VR headset device and are generated for energies above 10 MV.\n* Age 18 years or older at the time of consent.\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0-3 at the time of enrollment.\n* Ability to understand and the willingness to sign an IRB-approved informed consent document directly.\n\nExclusion Criteria:\n\n* Previous radiation therapy\n* VR device is determined to impede the radiation dosage during the VR device simulation and treatment planning\n* Participants with primary brain tumors, brain metastases, and cancer involving the sinuses, orbits, nose, or ears, are excluded from this clinical trial because the VR device may obstruct the area being treated\n* Participants with uncontrolled inter-current illness including but not limited to psychiatric illness\u002Fsocial situations that would limit compliance with study requirements per treating radiation oncologist.\n* Participants with known epilepsy, significant motion sickness, severe uncorrected visual impairment, severe uncorrected hearing impairment, or seizures, per participant report.\n* Participants with skin defects, infections, or open wounds in the area where the VR device is applied (face or scalp) or in the eyes per treating radiation oncologist.\n* Participants with pacemakers, internal defibrillators, hearing aid, or other implanted medical device. The Meta Quest device contains magnets and components that emit magnetic\u002Felectromagnetic fields which could affect the operation of nearby electronics and medical devices.\n\nRadiation Therapists:\n\nInclusion Criteria:\n\n* Agreement to participate after reviewing the information sheet\n* Radiation therapist at AHWFBCCC High Point who has treated at least one participant who enrolled on to the study and used the VR device.",{"count":164,"type":20},[23],"The purpose of this study is to evaluate the use and functionality of virtual reality (VR) during radiation therapy treatments for patients with prostate, breast, lung, or head and neck cancer.",[324,28],"Radiation Therapy",[28,326,324],"Cancer","2026-05-21",{"date":329,"type":41},"2026-05-22",{"date":331,"type":41},"2026-05-07",{"date":333,"type":20},"2029-02-01",{"name":335,"class":47},"Wake Forest University Health Sciences",{"id":337,"slug":4,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":4,"eligibilityCriteria":340,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":341,"enrollmentInfo":342,"targetDuration":4,"studyType":21,"phases":344,"briefSummary":345,"conditions":346,"keywords":348,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":350,"startDateStruct":351,"completionDateStruct":353,"leadSponsor":355,"locationsCount":102},"100558564","NCT06552754","Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers","* INCLUSION CRITERIA:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n* Provision of signed and dated informed consent form\n* Stated willingness to comply with all study procedures and availability for the duration of the study\n* Aged 18-60\n* Ability to read, speak, and write in English\n* Normal or corrected-to-normal hearing\n* Normal vision or corrected-to-normal without use of glasses. Contact lenses for corrective purposes are acceptable.\n\nAbility to read, speak and write in English is a requirement because the VR-based study materials and assessment are only available in English and several of the key questionnaires for the study are not validated in other languages.\n\nEXCLUSION CRITERIA:\n\nAn individual who meets any of the following criteria will be excluded from participation in this study:\n\n* Reporting motion sickness propensity of 0, 9 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants).\n* Reporting a history of photo-sensitive seizure disorders, vestibular disorders and\u002For other conditions that may make participants prone to nausea, dizziness, vertigo, ataxia, or incoordination.\n* Known pregnancy\n* Reporting current use of medication or supplements that inhibit nausea, e.g., Zofran\u002Fondansetron, Phenergan\u002Fpromethazine","60 Years",{"count":343,"type":20},150,[23],"Background:\n\nPeople use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have \"cybersickness\" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use.\n\nObjective:\n\nTo see if Motion Reset software can reduce cybersickness in people using VR.\n\nEligibility:\n\nHealthy adults aged 18 to 60 years.\n\nDesign:\n\nParticipants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers.\n\nThe study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups:\n\nGroup 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.\n\nGroup 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.\n\nGroup 3 will have no VR experience.\n\nParticipants will complete 2 questionnaires about their experiences in the first part of the study.\n\nFor the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort.\n\nAfter playing the game, participants will complete 12 questionnaires about their experience....",[347,28],"Healthy Volunteers",[347,28,349],"cybersickness",{"date":329,"type":41},{"date":352,"type":41},"2025-09-26",{"date":354,"type":20},"2027-02-01",{"name":356,"class":357},"National Human Genome Research Institute (NHGRI)","NIH",{"id":359,"slug":4,"hasResults":11,"nctId":360,"briefTitle":361,"officialTitle":361,"acronym":4,"eligibilityCriteria":362,"healthyVolunteers":11,"sex":363,"minAge":277,"maxAge":17,"enrollmentInfo":364,"targetDuration":4,"studyType":21,"phases":366,"briefSummary":367,"conditions":368,"keywords":370,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":77},"100596003","NCT07039799","The Effect of Virtual Reality Applications on Upper Extremity Functions in Patients With Duchenne Muscular Dystrophy","Inclusion Criteria:\n\n* Clinical diagnosis of Duchenne Muscular Dystrophy (DMD)\n* Age ≥ 7 years\n* Ambulatory or non-ambulatory status (both are eligible)\n* Ability to follow movement instructions\n* Brooke Upper Extremity Functional Rating Scale (BUEFS) level ≤ 4 (i.e., able to bring hand to mouth)\n\nExclusion Criteria:\n\n* Presence of any neurological diagnosis other than DMD\n* Cognitive, behavioral, or communication impairments that limit participation\n* Systemic illness or condition interfering with participation\n* Severe visual impairments incompatible with VR headset use\n* Presence of severe contractures or deformities that prevent execution of VR-based exercises","MALE",{"count":365,"type":20},36,[23],"This study aims to evaluate the effects of fully immersive virtual reality (VR) applications on upper extremity (UE) functions in individuals diagnosed with Duchenne Muscular Dystrophy (DMD). DMD is a progressive neuromuscular disorder that leads to muscle weakness and loss of function, including the upper limbs, which are essential for daily activities and independence.\n\nIn this randomized controlled trial, 36 participants with DMD will be divided into two groups: a control group receiving conventional physiotherapy and an intervention group receiving the same physiotherapy program (excluding upper extremity exercises) combined with VR-based exercises. The VR games will be designed specifically to improve shoulder, elbow, wrist, and hand functions and will be delivered using Meta Quest 3 headsets with hand-tracking capabilities.\n\nBoth groups will receive therapy twice a week for 8 weeks. Assessments will be conducted before and after the intervention, and at follow-up, using validated tools to measure UE function, grip strength, fine motor skills, trunk control, fatigue, quality of life, and participation in daily activities.\n\nThe study aims to explore innovative rehabilitation strategies for DMD and contribute to improving the independence and quality of life of affected individuals.",[369,28],"Duchenne Muscular Dystrophy (DMD)",[371,28,372],"Duchenne Muscular Dystrophy","Upper Extremity","2026-05-15",{"date":375,"type":41},"2026-05-19",{"date":377,"type":41},"2025-08-15",{"date":379,"type":20},"2027-08-15",{"name":381,"class":47},"Istanbul University",{"id":383,"slug":4,"hasResults":11,"nctId":384,"briefTitle":385,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":11,"sex":84,"minAge":109,"maxAge":136,"enrollmentInfo":388,"targetDuration":4,"studyType":21,"phases":390,"briefSummary":391,"conditions":392,"keywords":397,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":403,"completionDateStruct":405,"leadSponsor":406,"locationsCount":77},"100612214","NCT07250672","Patient-Specific 3D Action Observation Training in Parkinson's Disease","Examining the Effect of Action Observation Training Using Patient-Specific 3D Records in Parkinson's Patients","Inclusion Criteria:\n\n* Voluntary agreement to participate in the study\n* Clinical diagnosis of Parkinson's disease confirmed by a neurologist\n* Ongoing treatment with antiparkinsonian medication\n* Hoehn and Yahr (H-Y) stage ≤ 3\n* Ability to walk independently\n\nExclusion Criteria:\n\n* Presence of additional neurological disorders other than Parkinson's disease\n* Change in medication dosage within the past month\n* Score of ≥ 10 on the Simulator Sickness Questionnaire\n* Presence of amblyopia, strabismus, or pathologies impairing focus, depth perception, or normal 3D vision\n* Failure on the butterfly test of the Titmus stereotest (greater than 3,552 seconds of arc)",{"count":389,"type":20},24,[23],"Although studies exist demonstrating the effects of single-session action observation training on bradykinesia in patients with Parkinson's disease, research investigating the long-term application of such training remains limited. Furthermore, the broader literature indicates that action observation training has typically been conducted in simulated environments or by using recordings obtained from healthy individuals. The aim of the present study is to examine the effects of action observation training, delivered in a fully immersive virtual reality environment using each patient's own 3D motion recordings, on bradykinesia and other disease-related parameters.",[393,28,394,395,396],"Parkinson Disease","Action Obervation Training","Immersive Virtual Reality","3d Recording",[398,399],"Parkinson","Virtual reality","2026-05-06",{"date":402,"type":41},"2026-05-11",{"date":404,"type":41},"2025-12-15",{"date":379,"type":20},{"name":407,"class":47},"Abant Izzet Baysal University",{"id":409,"slug":4,"hasResults":11,"nctId":410,"briefTitle":411,"officialTitle":412,"acronym":413,"eligibilityCriteria":414,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":21,"phases":416,"briefSummary":417,"conditions":418,"keywords":422,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":426,"completionDateStruct":428,"leadSponsor":430,"locationsCount":4},"100636569","NCT07567391","Virtual Reality Therapy for Improving Caregiver and Patient Quality of Life in Home-Based Palliative Care in Saudi Arabia","Virtual Reality Nature Therapy for Palliative Patients and Caregivers in Saudi Arabia: A Randomized Controlled Trial to Support Quality of Life and Cultural Adaptation","VIRTIC-Hajj","Inclusion Criteria:\n\n* Adult patients (≥18 years) receiving palliative care in Saudi Arabia\n* Primary family caregivers living with and providing daily care to the patient\n* Ability to provide informed consent\n* Fluent in Arabic\n\nExclusion Criteria\n\n* Severe cognitive impairment or psychiatric conditions that prevent use of VR\n* History of epilepsy or vestibular disorders\n* Inability to understand or follow instructions for using VR equipment",{"count":187,"type":20},[23],"This randomized controlled trial evaluates the efficacy of a culturally adapted virtual reality (VR) nature therapy intervention aimed at improving the quality of life (QOL) and emotional well-being of palliative patients and their family caregivers in Saudi Arabia. The study involves immersive VR sessions depicting natural environments, including Saudi-specific landscapes, delivered to patient-caregiver dyads at home. Outcomes include self-reported QOL measures, psychophysiological parameters, and qualitative feedback.",[28,419,420,421],"Quality of Life","Palliative Care","Caregivers",[28,420,419,421],"2026-05-03",{"date":425,"type":41},"2026-05-05",{"date":427,"type":20},"2026-10-20",{"date":429,"type":20},"2027-09-01",{"name":431,"class":47},"University of Bisha",{"id":433,"slug":4,"hasResults":11,"nctId":434,"briefTitle":435,"officialTitle":436,"acronym":437,"eligibilityCriteria":438,"healthyVolunteers":108,"sex":84,"minAge":162,"maxAge":4,"enrollmentInfo":439,"targetDuration":4,"studyType":21,"phases":441,"briefSummary":442,"conditions":443,"keywords":448,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":454,"startDateStruct":455,"completionDateStruct":457,"leadSponsor":458,"locationsCount":4},"100601547","NCT07111910","Virtual Reality Infection Control Training for Healthcare Workers During the Hajj Season","Virtual Reality Training for Infection Control Preparedness in Healthcare Practitioners During Hajj: A Randomized Controlled Trial on Skill Acquisition and Clinical Readiness","(VIRTIC-Hajj)","Inclusion Criteria:\n\n* Aged 20 and above\n* Assigned to work in Hajj healthcare settings\n* Licensed healthcare worker (nurse, physician, EMT, etc.)\n* Able to provide informed consent\n* Fluent in Arabic or English\n\nExclusion Criteria:\n\n* History of epilepsy or motion sickness triggered by VR\n* Severe visual or cognitive impairments",{"count":440,"type":20},200,[23],"The goal of this clinical trial is to evaluate the effectiveness of immersive virtual reality (VR) training on improving infection control preparedness among healthcare workers during the Hajj pilgrimage in Saudi Arabia.\n\nThe main questions this study aims to answer are:\n\nDoes VR training improve healthcare workers' knowledge, confidence, and preparedness for infection control compared to traditional training?\n\nAre there differences in outcomes between the VR training and traditional lecture-based education?",[444,445,28,446,447],"Infection Control Training","Clinical Competence","Health Personnel","Mass Gathering Medicine",[449,450,451,452,453],"Virtual Reality Training","Infection Control","Hajj Pilgrimage","Healthcare Workers","Simulation Education",{"date":331,"type":41},{"date":456,"type":20},"2026-09-20",{"date":429,"type":20},{"name":431,"class":47},{"id":460,"slug":4,"hasResults":11,"nctId":461,"briefTitle":462,"officialTitle":463,"acronym":464,"eligibilityCriteria":465,"healthyVolunteers":11,"sex":84,"minAge":466,"maxAge":467,"enrollmentInfo":468,"targetDuration":4,"studyType":21,"phases":469,"briefSummary":470,"conditions":471,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":475,"startDateStruct":476,"completionDateStruct":478,"leadSponsor":480,"locationsCount":77},"100596178","NCT07042074","Use of Augmented Reality and Virtual Reality During Cognitive Behavioral Therapy for Needle Phobia","Use of a Spatial Computing Device and Augmented Reality and Virtual Reality for Exposure Therapy for Needle and Blood-Injection-Injury Phobia","SNAC","Inclusion Criteria:\n\n1. Patients between the ages of 11-17\n2. Fear of needle\n3. Patients screened with the modified APA severity Measure for Specific Phobia (blood, needles, or injections), and have an individual phobia score rated as moderate, severe, or extreme (as described below)\n\nExclusion Criteria:\n\n1. Legal guardian not present to obtain consent\n2. Adolescent with a significant neurological condition, or major developmental disability\n3. Adolescent with active infection of the face or hand\n4. A history of severe motion sickness\n5. A history of seizures caused by flashing light\n6. An impending surgery within the last 48 hours\n7. Adolescents who wear glasses and cannot use contacts\n8. Adolescents with physical disabilities that prevent them from using their hands\n9. Patients with substance use disorder in past year\n10. Virtual Reality headsets do not fit.","11 Years","17 Years",{"count":87,"type":20},[23],"This case series study seeks to evaluate the use of a Spatial Computing Device and Augmented Reality (AR) and Virtual Reality (VR) as an exposure therapy modality for children and adolescents with needle and blood-injection-injury phobia. This study will take place at Lucile Packard Children's Hospital (LPCH) and Stanford Hospital (Stanford University, Palo Alto, CA).",[472,28,473],"Needle Phobia","Cognitive Behavior Treatment","2026-05-02",{"date":331,"type":41},{"date":477,"type":20},"2026-05-01",{"date":479,"type":20},"2027-04-30",{"name":481,"class":47},"Stanford University",{"id":483,"slug":4,"hasResults":11,"nctId":484,"briefTitle":485,"officialTitle":486,"acronym":4,"eligibilityCriteria":487,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":488,"targetDuration":4,"studyType":21,"phases":489,"briefSummary":490,"conditions":491,"keywords":493,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":496,"lastUpdatePostDateStruct":497,"startDateStruct":498,"completionDateStruct":500,"leadSponsor":501,"locationsCount":77},"100558367","NCT06550193","Augmented Reality\u002FVirtual Reality (AR\u002FVR) for Ultrasound-guided Medical Procedures","The Use of Augmented Reality (AR) or Virtual Reality (VR) to Enhance the Precision and Accuracy of Ultrasound-guided Medical Procedures","Inclusion Criteria:\n\n* adult patients presenting for ultrasound-guided procedures, with ASA physical status I, II, or III.\n\nExclusion Criteria:\n\n* pregnancy\n* incarceration\n* BMI \\>35",{"count":187,"type":20},[23],"The study seeks to assess the efficacy of incorporating augmented reality (AR) or virtual reality (VR) technology into ultrasound-guided medical procedures such as regional anesthesia and line placement. By utilizing AR\u002FVR devices, the investigators will improve the ergonomics when using ultrasound to guide procedures. The aims are to enhance visualization of anatomical structures and improve procedural accuracy for clinicians. The study aims to evaluate the feasibility, and effectiveness of integrating AR\u002FVR technology into ultrasound-guided procedures, with the ultimate goal of improving patient outcomes.",[492,28],"Augmented Reality",[494,495],"ultrasound-guided procedure","nerve block","2026-04-30",{"date":331,"type":41},{"date":499,"type":41},"2025-09-30",{"date":178,"type":20},{"name":481,"class":47},{"id":503,"slug":4,"hasResults":11,"nctId":504,"briefTitle":505,"officialTitle":506,"acronym":4,"eligibilityCriteria":507,"healthyVolunteers":108,"sex":363,"minAge":17,"maxAge":4,"enrollmentInfo":508,"targetDuration":4,"studyType":21,"phases":510,"briefSummary":511,"conditions":512,"keywords":514,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":516,"lastUpdatePostDateStruct":517,"startDateStruct":518,"completionDateStruct":520,"leadSponsor":522,"locationsCount":77},"100597183","NCT07055178","Perioperative Virtual Reality Intervention for Pain and Anxiety During Vasectomies","A Perioperative Virtual Reality Intervention for Pain and Anxiety Management During Vasectomies: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 18 years of age or older.\n* Can speak and read English.\n* Have elected for a vasectomy.\n* Are scheduled to undergo their vasectomy under local anesthesia at the Men's Health Clinic\n\nExclusion Criteria:\n\n* Those who are not competent to provide informed consent (e.g., due to cognitive impairment).\n* Those who are unable to participate in a VR intervention (e.g., due to visual or auditory impairment).",{"count":509,"type":20},90,[23],"The goal of this clinical trial is to learn if a virtual reality (VR) program (TRIPP) can reduce pain, anxiety, and distress in adult men (aged 18+) undergoing a vasectomy under local anesthesia. The main questions it aims to answer are:\n\n* Does using VR during a vasectomy lower patients' pain during the procedure compared to standard care?\n* Does VR reduce anxiety and distress compared to standard care?\n* Are patients more satisfied with their experience when using VR compared to standard care?\n\nResearchers will compare two groups:\n\n* VR group: Patients will use a VR headset with a guided meditation program (TRIPP) during their vasectomy.\n* Control group: Patients will receive standard care (no VR).\n\nParticipants will:\n\n* Be randomly assigned to either the VR group or control group.\n* Complete brief questionnaires before, during, and after the procedure (about 15-20 minutes each time).\n* (VR group only) Use a VR headset during the procedure and provide optional feedback about the experience.\n\nWhy is this important? Vasectomies are typically done with local anesthesia (pain relief), but many patients still feel anxiety or discomfort. VR may help distract and relax patients, improving their experience. This study will help health professionals understand if VR could be a useful option for future patients.",[513,63,64,28],"Vasectomy",[28,515,513],"TRIPP","2026-04-28",{"date":425,"type":41},{"date":519,"type":41},"2025-07-02",{"date":521,"type":20},"2026-08",{"name":523,"class":47},"University of Manitoba",{"id":525,"slug":4,"hasResults":11,"nctId":526,"briefTitle":527,"officialTitle":528,"acronym":4,"eligibilityCriteria":529,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":530,"enrollmentInfo":531,"targetDuration":4,"studyType":21,"phases":532,"briefSummary":533,"conditions":534,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":536,"lastUpdatePostDateStruct":537,"startDateStruct":539,"completionDateStruct":541,"leadSponsor":543,"locationsCount":102},"100535160","NCT06248216","Virtual Reality Therapy for Cancer-Treatment Associated Symptoms","Implementation of an At-Home Multimodal Integrative Therapy Via Virtual Reality for Patients With Cancer-Treatment Associated Symptoms","Inclusion Criteria:\n\n* Adults ages 18-88\n* Cancer diagnosis (histology verified)\n* Had surgical intervention, completed chemotherapy or radiation for therapeutic purposes\n\n  -\\>3 months since last cancer treatment, but participants currently undergoing endocrine or immunotherapy treatments are permissible\n* Documented symptoms of cancer or cancer therapy including at least one of the following: pain, anxiety, sleep difficulty, fatigue, neuropathy\n* English speaker (written and spoken)\n\nExclusion Criteria:\n\n* Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years\n* Any personal (or family first degree) history of mania, schizophrenia, or other psychoses\n* Diagnosis and treatment of chronic pain, neuropathy, fatigue, sleep or anxiety disorder prior to cancer diagnosis\n* Current Hospice or palliative care only recipients\n* Color-blindness\n* Impaired or uncorrected hearing\n* Lifetime alcohol\u002Fdrug dependence or alcohol\u002Fdrug abuse in past 3 months\n* Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)\n* Known history of severe motion sickness\n* Pregnancy or breast feeding","88 Years",{"count":19,"type":20},[23],"We propose an innovative approach to symptom management in cancer patients following cancer treatments, utilizing a Multimodal Integrative Therapy (MIT) delivered via Virtual Reality (VR) program, authorized by the US Food and Drug Administration for in-home use. Our primary goal is to generate pilot data on the effects of MIT-VR program on pain, fatigue, sleep, depression, and anxiety in participants suffering from chronic cancer symptoms following cancer treatments.",[326,535,28],"Cancer Pain","2026-04-27",{"date":538,"type":41},"2026-04-29",{"date":540,"type":41},"2024-12-04",{"date":542,"type":20},"2027-12",{"name":544,"class":47},"University of Maryland, Baltimore",{"id":546,"slug":4,"hasResults":11,"nctId":547,"briefTitle":548,"officialTitle":548,"acronym":549,"eligibilityCriteria":550,"healthyVolunteers":11,"sex":84,"minAge":551,"maxAge":552,"enrollmentInfo":553,"targetDuration":4,"studyType":21,"phases":555,"briefSummary":556,"conditions":557,"keywords":561,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":565,"lastUpdatePostDateStruct":566,"startDateStruct":567,"completionDateStruct":568,"leadSponsor":570,"locationsCount":573},"100635877","NCT07558395","Effectiveness of a Visual Telerehabilitation Program on Visual Perception in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour","REVIIH-BT","Inclusion Criteria:\n\n* Male and Female\n* 10 - 40 years old\n* Diagnosed hemianopsia (\\>12 months)\n* History of diagnosis brain tumour\n* Being stable for the tumour for \\> 6 months (either on therapy or not)\n* Visual acuity ≤ 0.7 LogMAR\n* Ability to follow the visual and auditory stimuli and training instructions\n* Home WiFi access\n* Ability to attend all on site visits\n* Affiliation to the Social Security or beneficiary of such social protection\n\nExclusion Criteria:\n\n* Age\\\u003C 10 years old of \\> 40 years old\n* Ocular disease\n* Inability to perform during testing or training\n* 3 consecutive VRISE scores \\\u003C 25 at inclusion\n* History of vertigo\n* Prior vision rehabilitation interventions\n* Recreational or medicinal consumption of psychoactive drugs\n* Persons under court protection\n* Interpupillary distance \\\u003C 54mm","10 Years","40 Years",{"count":554,"type":20},120,[23],"Evaluate the efficiency of audiovisual stimulation in virtual reality for improving the visual perception of children, adolescents, and young adults with hemianopia resulting from pediatric brain tumors. These individuals can lose up to 50% of their visual field, significantly impacting their independence, mobility, and daily lives.",[558,28,559,560],"Hemianopsia","Visual Rehabilitation","Pediatric Brain Tumor",[562,563,564,31],"brain tumor","pediatric","visual rehabilitation","2026-04-23",{"date":496,"type":41},{"date":373,"type":20},{"date":569,"type":20},"2029-09",{"name":571,"class":572},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV",8,{"id":575,"slug":4,"hasResults":11,"nctId":576,"briefTitle":577,"officialTitle":577,"acronym":578,"eligibilityCriteria":579,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":580,"targetDuration":4,"studyType":21,"phases":582,"briefSummary":583,"conditions":584,"keywords":586,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":565,"lastUpdatePostDateStruct":589,"startDateStruct":590,"completionDateStruct":592,"leadSponsor":594,"locationsCount":77},"100635812","NCT07557550","Comparison of Two Relaxation Strategies Between Glasses, Virtual Reality Headset, and Without Relaxation Tool, in the Anxiety Preoperative of Orthopedic Adult Patients","RELAXPREOP","Inclusion Criteria:\n\n* Patient treated at the UAC D0\n* Orthopedic patient (arthroplasty mainly)\n* Anesthesic procedure with general anesthesia\n* Patient \\>18 years old without cognitive impairment in the investigator's judgment\n* Patient who has signed a free and informed consent\n* Patient affiliated to a social security scheme\n\nExclusion Criteria:\n\n* Patient with deafness that does not allow him to perceive and understand sounds\n* Patient with a visual impairment who does not allow him to watch and understand a video\n* Patient who does not master the French language (spoken, written and read)\n* Patient with a history of epilepsy\n* Patient with a history of migraine\u002Fheadache when using a virtual reality headset\n* Patients with a history of dizziness triggered by images (film, video game...)\n* Patient with untreated dry eye disease\n* Patient with psychiatric diseases and disorders not compatible with the study in the investigator's judgment\n* Patient who is pregnant, parturient, or breastfeeding.\n* Patient under guardianship or curatorship, under judicial protection or deprived of public law",{"count":581,"type":20},632,[23],"In adults, the prevalence of preoperative anxiety related to surgery or anesthesia ranges from 60 to 80%, and context plays an important role. Patients with significant preoperative anxiety experience reduced sleep quality. In addition, high preoperative anxiety is linked to more severe postoperative pain and an increased need for painkillers. In addition, it is a source of dysfunction in care. Currently, there are no recommendations regarding the prevention of preoperative anxiety. New approaches have emerged that show some benefit: music, binaural auditory stimulation and hypnosis. In the UAC J0 unit of the Amiens-Picardie University Hospital, the caregivers offer the PSiO glasses, a tool combining three techniques: light therapy, relaxation and chromotherapy. This system has obtained CE and FCC markings and seems to be more or less effective on patients admitted to the CH . A pilot study evaluating the effects of virtual reality hypnosis on patients' preoperative anxiety has shown that this technology represents a non-invasive way to reduce preoperative stress levels without side effects and without the need for additional medical or paramedical staff. This study aims to improve the patient's well-being before their operation. Depending on the randomization, he will benefit from a relaxation session with the Psio glasses or a virtual reality hypnosis session with the Hypno VR headset. Follow-up of patients will be carried out on the basis of variation in an anxiety scale, physiological criteria, the amount of anesthetic products used, the time spent in the recovery room, and the evaluation of pain.",[262,28,585],"Anxiety Preoperative",[587,31,588],"relaxation","anxiety preoperative",{"date":538,"type":41},{"date":591,"type":41},"2026-04-01",{"date":593,"type":20},"2027-04",{"name":202,"class":47},{"id":596,"slug":4,"hasResults":11,"nctId":597,"briefTitle":598,"officialTitle":599,"acronym":600,"eligibilityCriteria":601,"healthyVolunteers":11,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":602,"targetDuration":4,"studyType":21,"phases":604,"briefSummary":605,"conditions":606,"keywords":609,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":618,"lastUpdatePostDateStruct":619,"startDateStruct":620,"completionDateStruct":621,"leadSponsor":623,"locationsCount":77},"100627588","NCT07450586","Virtual Activities of Living for Occupational Rehabilitation","Virtual Activities of Living for Occupational Rehabilitation (VALOR)","VALOR","Criteria for inclusion:\n\n1. Participant has had a right or left hemispheric stroke affecting normal hand function.\n2. At least 3 months have passed since the last stroke.\n3. Participant has sufficient active finger flexion at the MCP joint in at least one finger to be detected by visual observation by a study therapist.\n4. Participant has visual acuity with corrective lenses of 20\u002F50 or better.\n5. Participant must have active movement against gravity of at least 30 degrees shoulder flexion, 45 degrees elbow flexion, elbow extension to within 30 degrees of full extension, and 15 degrees shoulder internal and external rotation.\n6. In the opinion of a study therapist, participant can independently and safely use the system at home or has an at-home caregiver who is willing and able to assist.\n7. In the opinion of a study therapist, participant has a suitable and safe space in their home for using the VALOR system.\n8. Participant is willing and able to provide informed consent.\n\nCriteria for exclusion:\n\n1. Withholding or withdrawal of consent by the participant.\n2. Inability to understand and follow verbal directions.\n3. Determination by the Principal Investigator that participation would result in overexertion or significant discomfort or pain.\n4. A psychological diagnosis that in the determination of the Principal Investigator could significantly impact subject's participation or that could be aggravated by study participation (Principal Investigator will consult with candidate's personal physician as appropriate).\n5. Determination by the Principal Investigator that participation would result in significant agitation or elevated stress.\n6. Visual field deficit in either eye that impairs the ability to view the VR display.\n7. Significant contractures of the muscles, joints, tendons, ligaments, or skin that restrict normal upper extremity movement.\n8. More than mild tone\u002Fspasticity (measured on modified Ashworth, 5-point scale);\n9. Severe pre-stroke co-morbidities, such as cardiovascular, neurological, orthopedic, or rheumatoid impairments before stroke that may interfere with task performance.\n10. Severe sensory deficits from the involved UE; or\n11. Hemispatial neglect that impairs the ability to process and perceive visual stimuli provided through the VR display.\n\nAs the system will be adaptable to a wide range of hand dexterity, no restriction will be made for fine control of digits. Patients will not be excluded due to inability to use the VR headset. If at any time the study therapist, in consultation with the Duke PI, determines the patient is not tolerating VR headset use, the patient will be given the option to use a non-immersive version of the VALOR system which employs a TV monitor and depth sensor in lieu of the headset. Please see Potential Risks section for additional details on controls and mitigations for potential cyber sickness.",{"count":603,"type":20},48,[23],"Duke University will serve as the clinical research site for the Phase II RCT of the VALOR system, which enables telehealth delivery of evidence-based upper extremity (UE) stroke therapy in a patient's home using immersive VR headset technology for guided practice of activities of daily living (ADLs) and instrumental ADLs (IADLs). The study compares VALOR Home Exercise Program (HEP) to Usual Care Treatment (UCT) in adults with stroke-related UE impairment.",[168,607,608,169,28],"Occupational Therapy","Activities of Daily Living",[610,28,372,611,612,608,613,614,615,616,617,607],"Stroke Rehabilitation","Telehealth","Home Exercise Program","Fugl-Meyer Assessment","Wolf Motor Function Test","Motor Activity Log","Hand Function","Hemiplegia","2026-04-22",{"date":536,"type":41},{"date":196,"type":20},{"date":622,"type":20},"2027-07-29",{"name":624,"class":625},"Barron Associates, Inc.","INDUSTRY",""]